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The exceptionally high reactivity of Cys 621 is critical for electrophilic activation of the sensory nerve ion channel TRPA1.
Bahia, Parmvir K; Parks, Thomas A; Stanford, Katherine R; Mitchell, David A; Varma, Sameer; Stevens, Stanley M; Taylor-Clark, Thomas E.
Afiliación
  • Bahia PK; Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL 33612.
  • Parks TA; Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL 33612.
  • Stanford KR; Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL 33612.
  • Mitchell DA; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612.
  • Varma S; Department of Cell Biology, Microbiology, and Molecular Biology, College of Arts and Sciences, University of South Florida, Tampa, FL 33620.
  • Stevens SM; Department of Cell Biology, Microbiology, and Molecular Biology, College of Arts and Sciences, University of South Florida, Tampa, FL 33620.
  • Taylor-Clark TE; Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL 33612 ttaylorc@health.usf.edu.
J Gen Physiol ; 147(6): 451-65, 2016 06.
Article en En | MEDLINE | ID: mdl-27241698
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Canales de Calcio / Activación del Canal Iónico / Cisteína / Canales de Potencial de Receptor Transitorio / Proteínas del Tejido Nervioso Límite: Humans Idioma: En Revista: J Gen Physiol Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Canales de Calcio / Activación del Canal Iónico / Cisteína / Canales de Potencial de Receptor Transitorio / Proteínas del Tejido Nervioso Límite: Humans Idioma: En Revista: J Gen Physiol Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos