Your browser doesn't support javascript.
loading
Comparison of the outcomes of hepatocellular carcinoma after hepatectomy between two regional medical centers in China and Japan.
Wang, Kai; Eguchi, Susumu; Hidaka, Masaaki; Jin, Tao; Soyama, Akihiko; Kuroki, Tamotsu; Huang, Mingwen; Wu, Linquan; Zou, Shubing; Shao, Jianghua.
Afiliación
  • Wang K; Department of Hepato-Biliary and Pancreatic Surgery, The Second Affiliated Hospital of Nanchang University, No.1 Minde Road, Nanchang 330006, PR China; Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.
  • Eguchi S; Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan. Electronic address: sueguchi@nagasaki-u.ac.jp.
  • Hidaka M; Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.
  • Jin T; Department of Hepato-Biliary and Pancreatic Surgery, The Second Affiliated Hospital of Nanchang University, No.1 Minde Road, Nanchang 330006, PR China.
  • Soyama A; Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.
  • Kuroki T; Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.
  • Huang M; Department of Hepato-Biliary and Pancreatic Surgery, The Second Affiliated Hospital of Nanchang University, No.1 Minde Road, Nanchang 330006, PR China.
  • Wu L; Department of Hepato-Biliary and Pancreatic Surgery, The Second Affiliated Hospital of Nanchang University, No.1 Minde Road, Nanchang 330006, PR China.
  • Zou S; Department of Hepato-Biliary and Pancreatic Surgery, The Second Affiliated Hospital of Nanchang University, No.1 Minde Road, Nanchang 330006, PR China.
  • Shao J; Department of Hepato-Biliary and Pancreatic Surgery, The Second Affiliated Hospital of Nanchang University, No.1 Minde Road, Nanchang 330006, PR China.
Asian J Surg ; 40(5): 380-388, 2017 Sep.
Article en En | MEDLINE | ID: mdl-27236717
BACKGROUND: Hepatocellular carcinoma (HCC) is a common malignant disease of the liver in China and Japan. The purpose of this study was to compare the outcomes of HCC patients after hepatectomy between two regional medical centers in China and Japan. METHODS: Data on HCC after hepatectomy were collected from January 2005 to December 2014 from Nagasaki University Hospital in Nagasaki, Japan and the Second Affiliated Hospital of Nanchang University in Nanchang, China. The patient and tumor characteristics, HCC etiology, and overall survival rates after hepatectomy were investigated. RESULTS: Two hundred patients in the Nagasaki group and 238 patients in the Nanchang group were diagnosed with HCC and underwent hepatectomy. The major underlying liver diseases were hepatitis C infection (32%, 64/200) and nonalcoholic steatohepatitis (NASH) (34.5%, 69/200) in the Nagasaki group, while in the Nanchang group, hepatitis B infection (79.4%, 189/238) was the dominant etiology. Large tumors (> 5 cm), the presence of a tumor capsule and a high alpha-fetoprotein value (≥ 400 U/L) were more frequently observed in the Nanchang group as compared with the Nagasaki group (p < 0.05). According to an outcome analysis, the Nanchang patients showed worse survival rates as compared with Nagasaki patients, particularly those with American Joint Committee on Cancer stages I and III due to the aggressive character of HCC in the Nanchang group. CONCLUSION: There are significant differences in the clinicopathologic features and outcomes of HCC patients from Japan and China. These differences may impact the eligibility for potentially curative therapy and the prognosis of patients with HCC.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Hepatectomía / Neoplasias Hepáticas Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies Límite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Asian J Surg Año: 2017 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Hepatectomía / Neoplasias Hepáticas Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies Límite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: Asian J Surg Año: 2017 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos