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Early Bunyavirus-Host Cell Interactions.
Albornoz, Amelina; Hoffmann, Anja B; Lozach, Pierre-Yves; Tischler, Nicole D.
Afiliación
  • Albornoz A; Molecular Virology Laboratory, Fundación Ciencia & Vida, Av. Zañartu 1482, 7780272 Santiago, Chile. aalbornoz@cienciavida.org.
  • Hoffmann AB; CellNetworks-Cluster of Excellence and Department of Infectious Diseases, Virology, University Hospital Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany. anja.hoffmann@uni-heidelberg.de.
  • Lozach PY; CellNetworks-Cluster of Excellence and Department of Infectious Diseases, Virology, University Hospital Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany. pierre-yves.lozach@med.uni-heidelberg.de.
  • Tischler ND; Molecular Virology Laboratory, Fundación Ciencia & Vida, Av. Zañartu 1482, 7780272 Santiago, Chile. ntischler@cienciavida.org.
Viruses ; 8(5)2016 05 24.
Article en En | MEDLINE | ID: mdl-27213430
The Bunyaviridae is the largest family of RNA viruses, with over 350 members worldwide. Several of these viruses cause severe diseases in livestock and humans. With an increasing number and frequency of outbreaks, bunyaviruses represent a growing threat to public health and agricultural productivity globally. Yet, the receptors, cellular factors and endocytic pathways used by these emerging pathogens to infect cells remain largely uncharacterized. The focus of this review is on the early steps of bunyavirus infection, from virus binding to penetration from endosomes. We address current knowledge and advances for members from each genus in the Bunyaviridae family regarding virus receptors, uptake, intracellular trafficking and fusion.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bunyaviridae / Acoplamiento Viral / Internalización del Virus / Interacciones Huésped-Patógeno Límite: Animals / Humans Idioma: En Revista: Viruses Año: 2016 Tipo del documento: Article País de afiliación: Chile Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bunyaviridae / Acoplamiento Viral / Internalización del Virus / Interacciones Huésped-Patógeno Límite: Animals / Humans Idioma: En Revista: Viruses Año: 2016 Tipo del documento: Article País de afiliación: Chile Pais de publicación: Suiza