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Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes.
Labenski, Verena; Suerth, Julia D; Barczak, Elke; Heckl, Dirk; Levy, Camille; Bernadin, Ornellie; Charpentier, Emmanuelle; Williams, David A; Fehse, Boris; Verhoeyen, Els; Schambach, Axel.
Afiliación
  • Labenski V; Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany.
  • Suerth JD; Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany.
  • Barczak E; Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany.
  • Heckl D; Department of Pediatric Hematology & Oncology, Hannover Medical School, Hannover, Germany; Department of Regulation in Infection Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
  • Levy C; CIRI, EVIR Team, Inserm, U1111, CNRS, UMR5308, Université de Lyon-1, ENS de Lyon, Lyon, France.
  • Bernadin O; CIRI, EVIR Team, Inserm, U1111, CNRS, UMR5308, Université de Lyon-1, ENS de Lyon, Lyon, France.
  • Charpentier E; Department of Regulation in Infection Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
  • Williams DA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Fehse B; Research Department Cell and Gene Therapy, Dept. of Stem Cell Transplantation, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
  • Verhoeyen E; CIRI, EVIR Team, Inserm, U1111, CNRS, UMR5308, Université de Lyon-1, ENS de Lyon, Lyon, France; Inserm, U1065, Centre Méditerranéen de Médecine Moléculaire (C3M), équipe "contrôle métabolique des morts cellulaires", Nice, France.
  • Schambach A; Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: schambach.axel@mh-hannover.de.
Biomaterials ; 97: 97-109, 2016 08.
Article en En | MEDLINE | ID: mdl-27162078
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T / Técnicas Genéticas / Alpharetrovirus / Ensamble de Virus / Vectores Genéticos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Biomaterials Año: 2016 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T / Técnicas Genéticas / Alpharetrovirus / Ensamble de Virus / Vectores Genéticos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Biomaterials Año: 2016 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Países Bajos