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Zika virus - emergence, evolution, pathology, diagnosis, and control: current global scenario and future perspectives - a comprehensive review.
Singh, Raj Kumar; Dhama, Kuldeep; Malik, Yashpal Singh; Ramakrishnan, Muthannan Andavar; Karthik, Kumaragurubaran; Tiwari, Ruchi; Saurabh, Sharad; Sachan, Swati; Joshi, Sunil Kumar.
Afiliación
  • Singh RK; a ICAR-Indian Veterinary Research Institute , Bareilly , India.
  • Dhama K; b Division of Pathology , ICAR-Indian Veterinary Research Institute , Bareilly , India.
  • Malik YS; c Division of Biological Standardization , ICAR-Indian Veterinary Research Institute , Bareilly , India.
  • Ramakrishnan MA; d Division of Virology , ICAR-Indian Veterinary Research Institute , Mukteswar Campus , Uttarakhand , India.
  • Karthik K; e Division of Bacteriology and Mycology , ICAR-Indian Veterinary Research Institute , Bareilly , India.
  • Tiwari R; f Department of Veterinary Microbiology and Immunology , College of Veterinary Sciences, Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwavidyalay Evum Go-Anusandhan Sansthan , Mathura , India.
  • Saurabh S; c Division of Biological Standardization , ICAR-Indian Veterinary Research Institute , Bareilly , India.
  • Sachan S; g Immunology Section , ICAR-Indian Veterinary Research Institute , Bareilly , India.
  • Joshi SK; h Cellular Immunology Lab, Frank Reidy Research Center for Bioelectrics, School of Medical Diagnostics & Translational Sciences , Old Dominion University , Norfolk , VA , USA.
Vet Q ; 36(3): 150-75, 2016 Sep.
Article en En | MEDLINE | ID: mdl-27158761
This review converses the Zika virus which has attained global concern due to its rapid pandemic potential and impact on humans. Though Zika virus was first isolated in 1947, till the recent large-scale outbreak which occurred in Micronesia, in 2007, the virus was placed into the innocuous pathogen category. The World Health Organization on 1 February 2016 declared it as a 'Public Health Emergency of International Concern.' Of the note, American as well as Pacific Island strains/isolates is relatively closer to Asian lineage strains. The African and American strains share more than 87.5% and 95% homologies with Asian strains/isolates, respectively. Asian strains form independent clusters, except those isolated from China, suggesting relatively more diversity than African strains. Prevention and control are mainly aimed at the vector population (mosquitoes) with Aedes aegypti being the main species. Surveys in Africa and Asia indicated seropositivity in various animal species. However, so far its natural reservoir is unknown. There is an urgent need to understand why Zika virus has shifted from being a virus that caused mild illness to unforeseen birth defects as well as autoimmune-neurological problems. Unfortunately, an effective vaccine is not available yet. Availability of cryo-electron microscopy based on 3.8 Å resolution revealing mature Zika virus structure and the probable virus attachment site to host cell would provide critical insights into the development of antiviral treatments and vaccines.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Virus Zika / Infección por el Virus Zika Tipo de estudio: Diagnostic_studies Idioma: En Revista: Vet Q Año: 2016 Tipo del documento: Article País de afiliación: India Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Virus Zika / Infección por el Virus Zika Tipo de estudio: Diagnostic_studies Idioma: En Revista: Vet Q Año: 2016 Tipo del documento: Article País de afiliación: India Pais de publicación: Reino Unido