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Inhibition of DPP4 activity in humans establishes its in vivo role in CXCL10 post-translational modification: prospective placebo-controlled clinical studies.
Decalf, Jérémie; Tarbell, Kristin V; Casrouge, Armanda; Price, Jeffrey D; Linder, Grace; Mottez, Estelle; Sultanik, Philippe; Mallet, Vincent; Pol, Stanislas; Duffy, Darragh; Albert, Matthew L.
Afiliación
  • Decalf J; The Laboratory of Dendritic Cell Immunobiology, Institut Pasteur, Paris, France INSERM U818, Paris, France.
  • Tarbell KV; Diabetes Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Casrouge A; The Laboratory of Dendritic Cell Immunobiology, Institut Pasteur, Paris, France INSERM U818, Paris, France.
  • Price JD; Diabetes Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Linder G; Diabetes Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Mottez E; Center for Human Immunology, Institut Pasteur, Paris, France.
  • Sultanik P; Département d'Hépatologie, AP-HP, Hôpital Cochin, Université Paris Descartes, INSERM UMS20, Institut Pasteur, Paris, France.
  • Mallet V; Département d'Hépatologie, AP-HP, Hôpital Cochin, Université Paris Descartes, INSERM UMS20, Institut Pasteur, Paris, France.
  • Pol S; Département d'Hépatologie, AP-HP, Hôpital Cochin, Université Paris Descartes, INSERM UMS20, Institut Pasteur, Paris, France.
  • Duffy D; The Laboratory of Dendritic Cell Immunobiology, Institut Pasteur, Paris, France INSERM U818, Paris, France Center for Human Immunology, Institut Pasteur, Paris, France darragh.duffy@pasteur.fr albertm@pasteur.fr.
  • Albert ML; The Laboratory of Dendritic Cell Immunobiology, Institut Pasteur, Paris, France INSERM U818, Paris, France Center for Human Immunology, Institut Pasteur, Paris, France Department of Cancer Immunotherapy, Genentech, South San Francisco, CA, USA darragh.duffy@pasteur.fr albertm@pasteur.fr.
EMBO Mol Med ; 8(6): 679-83, 2016 06.
Article en En | MEDLINE | ID: mdl-27137491
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Procesamiento Proteico-Postraduccional / Dipeptidil Peptidasa 4 / Quimiocina CXCL10 / Inhibidores de la Dipeptidil-Peptidasa IV / Fosfato de Sitagliptina Tipo de estudio: Clinical_trials / Observational_studies Límite: Humans Idioma: En Revista: EMBO Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2016 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Procesamiento Proteico-Postraduccional / Dipeptidil Peptidasa 4 / Quimiocina CXCL10 / Inhibidores de la Dipeptidil-Peptidasa IV / Fosfato de Sitagliptina Tipo de estudio: Clinical_trials / Observational_studies Límite: Humans Idioma: En Revista: EMBO Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2016 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido