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Sphingosine-1-phosphate phosphatase 2 promotes disruption of mucosal integrity, and contributes to ulcerative colitis in mice and humans.
Huang, Wei-Ching; Liang, Jie; Nagahashi, Masayuki; Avni, Dorit; Yamada, Akimitsu; Maceyka, Michael; Wolen, Aaron R; Kordula, Tomasz; Milstien, Sheldon; Takabe, Kazuaki; Oravecz, Tamas; Spiegel, Sarah.
Afiliación
  • Huang WC; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, School of Medicine and the Massey Cancer Center, Richmond, Virginia, USA;
  • Liang J; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, School of Medicine and the Massey Cancer Center, Richmond, Virginia, USA;
  • Nagahashi M; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, School of Medicine and the Massey Cancer Center, Richmond, Virginia, USA; Division of Surgical Oncology, Department of Surgery, Virginia Commonwealth University, School of Medicine and the Massey Cancer Center, Richm
  • Avni D; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, School of Medicine and the Massey Cancer Center, Richmond, Virginia, USA;
  • Yamada A; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, School of Medicine and the Massey Cancer Center, Richmond, Virginia, USA; Division of Surgical Oncology, Department of Surgery, Virginia Commonwealth University, School of Medicine and the Massey Cancer Center, Richm
  • Maceyka M; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, School of Medicine and the Massey Cancer Center, Richmond, Virginia, USA;
  • Wolen AR; Center for Clinical and Translational Research, Virginia Commonwealth University, School of Medicine and the Massey Cancer Center, Richmond, Virginia, USA;
  • Kordula T; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, School of Medicine and the Massey Cancer Center, Richmond, Virginia, USA;
  • Milstien S; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, School of Medicine and the Massey Cancer Center, Richmond, Virginia, USA;
  • Takabe K; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, School of Medicine and the Massey Cancer Center, Richmond, Virginia, USA; Division of Surgical Oncology, Department of Surgery, Virginia Commonwealth University, School of Medicine and the Massey Cancer Center, Richm
  • Oravecz T; Lexicon Pharmaceuticals, The Woodlands, Texas, USA.
  • Spiegel S; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, School of Medicine and the Massey Cancer Center, Richmond, Virginia, USA; sarah.spiegel@vcuhelath.org.
FASEB J ; 30(8): 2945-58, 2016 08.
Article en En | MEDLINE | ID: mdl-27130484
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Colitis Ulcerosa / Monoéster Fosfórico Hidrolasas / Mucosa Intestinal / Proteínas de la Membrana Límite: Animals / Humans Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Colitis Ulcerosa / Monoéster Fosfórico Hidrolasas / Mucosa Intestinal / Proteínas de la Membrana Límite: Animals / Humans Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos