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Tonsillectomy in adults with obstructive sleep apnea.
Holmlund, Thorbjörn; Franklin, Karl A; Levring Jäghagen, Eva; Lindkvist, Marie; Larsson, Torbjörn; Sahlin, Carin; Berggren, Diana.
Afiliación
  • Holmlund T; Department of Clinical Sciences/Otorhinolaryngology, Umeå University, Umeå, Sweden.
  • Franklin KA; Department of Surgical and Perioperative Sciences/Surgery, Umeå University, Umeå, Sweden.
  • Levring Jäghagen E; Department of Odontology/Oral and Maxillofacial Radiology, Umeå University, Umeå, Sweden.
  • Lindkvist M; Department of Umeå School of Business and Economics/Statistics, Umeå University, Umeå, Sweden.
  • Larsson T; Department of Public Health and Clinical Medicine/Epidemiology and Global Health, Umeå University, Umeå, Sweden.
  • Sahlin C; Department of Clinical Sciences/Otorhinolaryngology, Umeå University, Umeå, Sweden.
  • Berggren D; Department of Public Health and Clinical Medicine/Medicine, Umeå University, Umeå, Sweden.
Laryngoscope ; 126(12): 2859-2862, 2016 12.
Article en En | MEDLINE | ID: mdl-27107408
OBJECTIVES/HYPOTHESIS: To study whether tonsillectomy is effective on obstructive sleep apnea (OSA) in adults with large tonsils. STUDY DESIGN: A multicenter prospective interventional study. METHODS: The study comprised 28 patients with OSA, an apnea-hypopnea index of > 10, large tonsils (Friedman tonsil size 3 and 4), and age 18 to 59 years. They were derived from 41 consecutive males and females with large tonsils referred for a suspicion of sleep apnea to the ear, nose, and throat departments in Umeå, Skellefteå, and Sunderbyn in northern Sweden. The primary outcome was the apnea-hypopnea index, measured with polygraphic sleep apnea recordings 6 months after surgery. Secondary outcomes included daytime sleepiness, as measured with the Epworth Sleepiness Scale, and swallowing function, using video-fluoroscopy. RESULTS: The apnea-hypopnea index was reduced from a mean of 40 units per hour (95% confidence interval [CI] 28-51) to seven units per hour (95% CI 3-11), P < 0.001, at the 6-month follow-up after surgery. The apnea-hypopnea index was reduced in all patients and 18 (64%) were cured. The Epworth Sleepiness Scale was reduced from a mean of 11 (95% CI 8-13) to 6.0 (95% CI 4-7), P < 0.001. A swallowing dysfunction was found in seven of eight investigated patients before surgery. Of those, swallowing function improved in five patients after surgery, whereas no one deteriorated. CONCLUSION: Tonsillectomy may be effective treatment for adult patients with OSA and large tonsils. Tonsillectomy may be suggested for adults with OSA and large tonsils. LEVEL OF EVIDENCE: 4. Laryngoscope, 126:2859-2862, 2016.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tonsila Palatina / Tonsilectomía / Apnea Obstructiva del Sueño Tipo de estudio: Clinical_trials / Observational_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Laryngoscope Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tonsila Palatina / Tonsilectomía / Apnea Obstructiva del Sueño Tipo de estudio: Clinical_trials / Observational_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Laryngoscope Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Estados Unidos