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The International Dimension of the U.S. HIV Transmission Network and Onward Transmission of HIV Recently Imported into the United States.
Wertheim, Joel O; Oster, Alexandra M; Hernandez, Angela L; Saduvala, Neeraja; Bañez Ocfemia, M Cheryl; Hall, H Irene.
Afiliación
  • Wertheim JO; 1 Department of Medicine, University of California , San Diego, San Diego, California.
  • Oster AM; 2 ICF International , Atlanta, Georgia .
  • Hernandez AL; 3 Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention , Atlanta, Georgia .
  • Saduvala N; 3 Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention , Atlanta, Georgia .
  • Bañez Ocfemia MC; 2 ICF International , Atlanta, Georgia .
  • Hall HI; 3 Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention , Atlanta, Georgia .
AIDS Res Hum Retroviruses ; 32(10-11): 1046-1053, 2016.
Article en En | MEDLINE | ID: mdl-27105549
The majority of HIV infections in the United States can be traced back to a single introduction in late 1960s or early 1970s. However, it remains unclear whether subsequent introductions of HIV into the United States have given rise to onward transmission. Genetic transmission networks can aid in understanding HIV transmission. We constructed a genetic distance-based transmission network using HIV-1 pol sequences reported to the U.S. National HIV Surveillance System (n = 41,539) and all publicly available non-U.S. HIV-1 pol sequences (n = 86,215). Of the 13,145 U.S. persons clustered in the network, 457 (3.5%) were genetically linked to a potential transmission partner outside the United States. For internationally connected persons residing in but born outside the United States, 61% had a connection to their country of birth or to another country that shared a language with their country of birth. Bayesian molecular clock phylogenetic analyses indicate that introduced nonsubtype B infections have resulted in onward transmission within the United States.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / VIH-1 / Genotipo Límite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: America do norte Idioma: En Revista: AIDS Res Hum Retroviruses Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / VIH-1 / Genotipo Límite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: America do norte Idioma: En Revista: AIDS Res Hum Retroviruses Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos