Computational spatiotemporal analysis identifies WAVE2 and cofilin as joint regulators of costimulation-mediated T cell actin dynamics.

Roybal, Kole T; Buck, Taráz E; Ruan, Xiongtao; Cho, Baek Hwan; Clark, Danielle J; Ambler, Rachel; Tunbridge, Helen M; Zhang, Jianwei; Verkade, Paul; Wülfing, Christoph; Murphy, Robert F

Roybal, Kole T; Buck, Taráz E; Ruan, Xiongtao; Cho, Baek Hwan; Clark, Danielle J; Ambler, Rachel; Tunbridge, Helen M; Zhang, Jianwei; Verkade, Paul; Wülfing, Christoph; Murphy, Robert F.

Afiliación

Roybal KT; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK. Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Buck TE; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
Ruan X; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
Cho BH; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
Clark DJ; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK.
Ambler R; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK.
Tunbridge HM; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK.
Zhang J; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
Verkade P; School of Biochemistry, University of Bristol, Bristol BS8 1TD, UK.
Wülfing C; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK. Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. christoph.wuelf
Murphy RF; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA. Departments of Biological Sciences, Biomedical Engineering, and Machine Learning, Carnegie Mellon University, Pittsburgh, PA 15213, USA. Freiburg Institute for Advanced Studies and Fa

Sci Signal ; 9(424): rs3, 2016 Apr 19.

Article en En | MEDLINE | ID: mdl-27095595

Asunto(s)

Citoesqueleto de Actina/metabolismo; Factores Despolimerizantes de la Actina/metabolismo; Biología Computacional/métodos; Linfocitos T/metabolismo; Familia de Proteínas del Síndrome de Wiskott-Aldrich/metabolismo; Factores Despolimerizantes de la Actina/genética; Animales; Western Blotting; Antígenos CD28/genética; Antígenos CD28/metabolismo; Células Cultivadas; Proteínas Fluorescentes Verdes/genética; Proteínas Fluorescentes Verdes/metabolismo; Sinapsis Inmunológicas/metabolismo; Cinética; Activación de Linfocitos; Ratones Transgénicos; Microscopía Fluorescente; Receptores de Antígenos de Linfocitos T/genética; Receptores de Antígenos de Linfocitos T/metabolismo; Transducción de Señal; Imagen de Lapso de Tiempo/métodos; Familia de Proteínas del Síndrome de Wiskott-Aldrich/genética

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Citoesqueleto de Actina / Linfocitos T / Biología Computacional / Factores Despolimerizantes de la Actina / Familia de Proteínas del Síndrome de Wiskott-Aldrich Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Sci Signal Asunto de la revista: CIENCIA / FISIOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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