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Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence.
Balko, Justin M; Schwarz, Luis J; Luo, Na; Estrada, Mónica V; Giltnane, Jennifer M; Dávila-González, Daniel; Wang, Kai; Sánchez, Violeta; Dean, Phillip T; Combs, Susan E; Hicks, Donna; Pinto, Joseph A; Landis, Melissa D; Doimi, Franco D; Yelensky, Roman; Miller, Vincent A; Stephens, Phillip J; Rimm, David L; Gómez, Henry; Chang, Jenny C; Sanders, Melinda E; Cook, Rebecca S; Arteaga, Carlos L.
Afiliación
  • Balko JM; Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA. Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232, USA. Breast Cancer Research Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA. carlos.arteaga@vanderbilt.edu just
  • Schwarz LJ; Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA.
  • Luo N; Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA.
  • Estrada MV; Breast Cancer Research Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA. Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN 37232, USA.
  • Giltnane JM; Breast Cancer Research Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA. Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN 37232, USA.
  • Dávila-González D; Houston Methodist Cancer Center, Houston, TX 77030, USA.
  • Wang K; Foundation Medicine, Cambridge, MA 02142, USA.
  • Sánchez V; Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA.
  • Dean PT; Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA.
  • Combs SE; Departments of Pathology and Medicine, Yale University, New Haven, CT 06520, USA.
  • Hicks D; Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232, USA.
  • Pinto JA; Oncosalud, Lima 41, Perú.
  • Landis MD; Houston Methodist Cancer Center, Houston, TX 77030, USA.
  • Doimi FD; Instituto Nacional de Enfermedades Neoplásicas (INEN), Lima 34, Perú.
  • Yelensky R; Foundation Medicine, Cambridge, MA 02142, USA.
  • Miller VA; Foundation Medicine, Cambridge, MA 02142, USA.
  • Stephens PJ; Foundation Medicine, Cambridge, MA 02142, USA.
  • Rimm DL; Departments of Pathology and Medicine, Yale University, New Haven, CT 06520, USA.
  • Gómez H; Instituto Nacional de Enfermedades Neoplásicas (INEN), Lima 34, Perú.
  • Chang JC; Houston Methodist Cancer Center, Houston, TX 77030, USA.
  • Sanders ME; Breast Cancer Research Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA. Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN 37232, USA.
  • Cook RS; Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232, USA. Breast Cancer Research Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA.
  • Arteaga CL; Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA. Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232, USA. Breast Cancer Research Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA. carlos.arteaga@vanderbilt.edu just
Sci Transl Med ; 8(334): 334ra53, 2016 Apr 13.
Article en En | MEDLINE | ID: mdl-27075627
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cromosomas Humanos Par 9 / Amplificación de Genes / Janus Quinasa 2 / Sitios Genéticos / Neoplasias de la Mama Triple Negativas Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cromosomas Humanos Par 9 / Amplificación de Genes / Janus Quinasa 2 / Sitios Genéticos / Neoplasias de la Mama Triple Negativas Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos