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Real Time Gabor-Domain Optical Coherence Microscopy for 3D Imaging.
Rolland, Jannick P; Canavesi, Cristina; Tankam, Patrice; Cogliati, Andrea; Lanis, Mara; Santhanam, Anand P.
Afiliación
  • Rolland JP; University of Rochester, Rochester, NY, USA 14627.
  • Canavesi C; LighTopTech Corp., West Henrietta, NY, USA 14586.
  • Tankam P; University of Rochester, Rochester, NY, USA 14627.
  • Cogliati A; University of Rochester, Rochester, NY, USA 14627.
  • Lanis M; University of Rochester, Rochester, NY, USA 14627.
  • Santhanam AP; University of California, Los Angeles, CA, USA 90095.
Stud Health Technol Inform ; 220: 335-40, 2016.
Article en En | MEDLINE | ID: mdl-27046601
Fast, robust, nondestructive 3D imaging is needed for the characterization of microscopic tissue structures across various clinical applications. A custom microelectromechanical system (MEMS)-based 2D scanner was developed to achieve, together with a multi-level GPU architecture, 55 kHz fast-axis A-scan acquisition in a Gabor-domain optical coherence microscopy (GD-OCM) custom instrument. GD-OCM yields high-definition micrometer-class volumetric images. A dynamic depth of focusing capability through a bio-inspired liquid lens-based microscope design, as in whales' eyes, was developed to enable the high definition instrument throughout a large field of view of 1 mm3 volume of imaging. Developing this technology is prime to enable integration within the workflow of clinical environments. Imaging at an invariant resolution of 2 µm has been achieved throughout a volume of 1 × 1 × 0.6 mm3, acquired in less than 2 minutes. Volumetric scans of human skin in vivo and an excised human cornea are presented.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Procesamiento de Señales Asistido por Computador / Aumento de la Imagen / Imagenología Tridimensional / Tomografía de Coherencia Óptica / Sistemas Microelectromecánicos / Microscopía Tipo de estudio: Diagnostic_studies Idioma: En Revista: Stud Health Technol Inform Asunto de la revista: INFORMATICA MEDICA / PESQUISA EM SERVICOS DE SAUDE Año: 2016 Tipo del documento: Article Pais de publicación: Países Bajos
Buscar en Google
Añadir a Mi BVS
Imprimir
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Procesamiento de Señales Asistido por Computador / Aumento de la Imagen / Imagenología Tridimensional / Tomografía de Coherencia Óptica / Sistemas Microelectromecánicos / Microscopía Tipo de estudio: Diagnostic_studies Idioma: En Revista: Stud Health Technol Inform Asunto de la revista: INFORMATICA MEDICA / PESQUISA EM SERVICOS DE SAUDE Año: 2016 Tipo del documento: Article Pais de publicación: Países Bajos