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Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes.
Bacos, Karl; Gillberg, Linn; Volkov, Petr; Olsson, Anders H; Hansen, Torben; Pedersen, Oluf; Gjesing, Anette Prior; Eiberg, Hans; Tuomi, Tiinamaija; Almgren, Peter; Groop, Leif; Eliasson, Lena; Vaag, Allan; Dayeh, Tasnim; Ling, Charlotte.
Afiliación
  • Bacos K; Epigenetics and Diabetes Unit, Department of Clinical Sciences, Lund University Diabetes Centre, CRC 91:12, Jan Waldenströms gata 35, 20502 Malmö, Sweden.
  • Gillberg L; Department of Endocrinology, Diabetes and Metabolism, Rigshospitalet, Tagensvej 20, 2200 Copenhagen, Denmark.
  • Volkov P; Faculty of Health Sciences, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen, Denmark.
  • Olsson AH; Epigenetics and Diabetes Unit, Department of Clinical Sciences, Lund University Diabetes Centre, CRC 91:12, Jan Waldenströms gata 35, 20502 Malmö, Sweden.
  • Hansen T; Department of Endocrinology, Diabetes and Metabolism, Rigshospitalet, Tagensvej 20, 2200 Copenhagen, Denmark.
  • Pedersen O; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Universitetsparken 1, 2100 Copenhagen, Denmark.
  • Gjesing AP; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Universitetsparken 1, 2100 Copenhagen, Denmark.
  • Eiberg H; The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, University of Copenhagen, Universitetsparken 1, 2100 Copenhagen, Denmark.
  • Tuomi T; Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen, Denmark.
  • Almgren P; Department of Endocrinology, Abdominal Centre, Helsinki University Hospital; Folkhalsan Research Center; Research Program for Diabetes and Obesity, Hartmaninkatu 8, Helsinki 00014, Finland.
  • Groop L; Finnish Institute for Molecular Medicine, University of Helsinki, Hartmaninkatu 8, 00014 Helsinki, Finland.
  • Eliasson L; Diabetes and Endocrinology, Department of Clinical Sciences, Lund University Diabetes Centre, Jan Waldenströms gata 35, 20502 Malmö, Sweden.
  • Vaag A; Finnish Institute for Molecular Medicine, University of Helsinki, Hartmaninkatu 8, 00014 Helsinki, Finland.
  • Dayeh T; Diabetes and Endocrinology, Department of Clinical Sciences, Lund University Diabetes Centre, Jan Waldenströms gata 35, 20502 Malmö, Sweden.
  • Ling C; Islet cell exocytosis, Department of Clinical Sciences, Lund University Diabetes Centre, Jan Waldenströms gata 35, 20502 Malmö, Sweden.
Nat Commun ; 7: 11089, 2016 Mar 31.
Article en En | MEDLINE | ID: mdl-27029739
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Islotes Pancreáticos / Diabetes Mellitus Tipo 2 / Epigenómica / Insulina Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Humans / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2016 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Islotes Pancreáticos / Diabetes Mellitus Tipo 2 / Epigenómica / Insulina Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Humans / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2016 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Reino Unido