[EFFECT OF NEONATAL SEIZURES ON THE SYNAPTIC PLASTICITY OF RAT SOMATOSENSORY CORTEX].
Fiziol Zh (1994)
; 61(6): 11-6, 2015.
Article
en Uk
| MEDLINE
| ID: mdl-27025040
Using an experimental model of neonatal recurrent seizures we investigated the influence of epileptic seizures in the various forms of synaptic plasticity in neurons of the somatosensory cortex. We found that early seizures do not affect the post-tetanic potentiation of the amplitude of the postsynaptic potentials and the depression of postsynaptic potentials during high-frequency stimulation. However they result in the chronic increase of the long-term potentiation of synaptic transmission. These changes of synaptic plasticity may affect the processing of the sensory information in patients with a history of recurrent seizures during early development.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Corteza Somatosensorial
/
Potenciación a Largo Plazo
/
Transmisión Sináptica
/
Epilepsia
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
/
Male
Idioma:
Uk
Revista:
Fiziol Zh (1994)
Año:
2015
Tipo del documento:
Article
Pais de publicación:
Ucrania