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Ascorbic acid serum levels are reduced in patients with hematological malignancies.
Huijskens, Mirelle J A J; Wodzig, Will K W H; Walczak, Mateusz; Germeraad, Wilfred T V; Bos, Gerard M J.
Afiliación
  • Huijskens MJ; Department of Internal Medicine, Division of Hematology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Wodzig WK; Department of Clinical Chemistry, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Walczak M; Department of Internal Medicine, Division of Hematology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Germeraad WT; Department of Internal Medicine, Division of Hematology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Bos GM; Department of Internal Medicine, Division of Hematology, Maastricht University Medical Center, Maastricht, The Netherlands.
Results Immunol ; 6: 8-10, 2016.
Article en En | MEDLINE | ID: mdl-27014565
In this paper we demonstrate that patients treated with chemotherapy and/or hematopoietic stem cell transplantation (HSCT) have highly significant reduced serum ascorbic acid (AA) levels compared to healthy controls. We recently observed in in vitro experiments that growth of both T and NK cells from hematopoietic stem cells is positively influenced by AA. It might be of clinical relevance to study the function and recovery of immune cells after intensive treatment, its correlation to AA serum levels and the possible effect of AA supplementation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Results Immunol Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Results Immunol Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Países Bajos