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Availability of applying diaphragm matching with the breath-holding technique in stereotactic body radiation therapy for liver tumors.
Kawahara, Daisuke; Ozawa, Shuichi; Kimura, Tomoki; Nakashima, Takeo; Aita, Masamichi; Tsuda, Shintaro; Ochi, Yusuke; Okumura, Takuro; Masuda, Hirokazu; Ohno, Yoshimi; Murakami, Yuji; Nagata, Yasushi.
Afiliación
  • Kawahara D; Section of Radiation Therapy, Department of Clinical Support, Hiroshima University Hospital, 1-2-3, Kasumi, Minami-ku, Hiroshima City 734-8551, Japan; Course of Medical and Dental Sciences, Graduate School of Biomedical & Health Sciences, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima
  • Ozawa S; Department of Radiation Oncology, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima City 734-8551, Japan.
  • Kimura T; Department of Radiation Oncology, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima City 734-8551, Japan.
  • Nakashima T; Department of Radiation Oncology, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima City 734-8551, Japan.
  • Aita M; Section of Radiation Therapy, Department of Clinical Support, Hiroshima University Hospital, 1-2-3, Kasumi, Minami-ku, Hiroshima City 734-8551, Japan.
  • Tsuda S; Section of Radiation Therapy, Department of Clinical Support, Hiroshima University Hospital, 1-2-3, Kasumi, Minami-ku, Hiroshima City 734-8551, Japan.
  • Ochi Y; Section of Radiation Therapy, Department of Clinical Support, Hiroshima University Hospital, 1-2-3, Kasumi, Minami-ku, Hiroshima City 734-8551, Japan.
  • Okumura T; Section of Radiation Therapy, Department of Clinical Support, Hiroshima University Hospital, 1-2-3, Kasumi, Minami-ku, Hiroshima City 734-8551, Japan.
  • Masuda H; Section of Radiation Therapy, Department of Clinical Support, Hiroshima University Hospital, 1-2-3, Kasumi, Minami-ku, Hiroshima City 734-8551, Japan.
  • Ohno Y; Section of Radiation Therapy, Department of Clinical Support, Hiroshima University Hospital, 1-2-3, Kasumi, Minami-ku, Hiroshima City 734-8551, Japan.
  • Murakami Y; Department of Radiation Oncology, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima City 734-8551, Japan.
  • Nagata Y; Department of Radiation Oncology, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima City 734-8551, Japan.
Phys Med ; 32(4): 557-61, 2016 Apr.
Article en En | MEDLINE | ID: mdl-27012541
PURPOSE: Image-guided radiotherapy (IGRT) based on bone matching can produce large target-positioning errors because of expiration breath-hold reproducibility during stereotactic body radiation therapy (SBRT) for liver tumors. Therefore, the feasibility of diaphragm-based 3D image matching between planning computed tomography (CT) and pretreatment cone-beam CT was investigated. METHODS: In 59 liver SBRT cases, Lipiodol uptake after transarterial chemoembolization was defined as a tumor marker. Further, the relative isocenter coordinate that was obtained by Lipiodol matching was defined as the reference coordinate. The distance between the relative isocenter coordinate and reference coordinate, which was obtained from diaphragm matching and bone matching techniques, was defined as the target positioning error. Furthermore, the target positioning error between liver matching and Lipiodol matching was evaluated. RESULTS: The positioning errors in all directions by the diaphragm matching were significantly smaller than those obtained by using by the bone matching technique (p < 0.05). Further, the positioning errors in the A-P and C-C directions that were obtained by using liver matching were significantly smaller than those obtained by using bone matching (p < 0.05). The estimated PTV margins calculated by the formula proposed by van Herk for diaphragm matching, liver matching, and bone matching were 5.0 mm, 5.0 mm, and 11.6 mm in the C-C direction; 3.6 mm, 2.4 mm, and 6.9 mm in the A-P direction; and 2.6 mm, 4.1 mm, and 4.6 mm in the L-R direction, respectively. CONCLUSIONS: Diaphragm matching-based IGRT may be an alternative image matching technique for determining liver tumor positions in patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Planificación de la Radioterapia Asistida por Computador / Diafragma / Radiocirugia / Carcinoma Hepatocelular / Neoplasias Hepáticas Límite: Aged / Aged80 / Humans / Middle aged Idioma: En Revista: Phys Med Asunto de la revista: BIOFISICA / BIOLOGIA / MEDICINA Año: 2016 Tipo del documento: Article Pais de publicación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Planificación de la Radioterapia Asistida por Computador / Diafragma / Radiocirugia / Carcinoma Hepatocelular / Neoplasias Hepáticas Límite: Aged / Aged80 / Humans / Middle aged Idioma: En Revista: Phys Med Asunto de la revista: BIOFISICA / BIOLOGIA / MEDICINA Año: 2016 Tipo del documento: Article Pais de publicación: Italia