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Imaging Mass Spectrometry Reveals Acyl-Chain- and Region-Specific Sphingolipid Metabolism in the Kidneys of Sphingomyelin Synthase 2-Deficient Mice.
Sugimoto, Masayuki; Wakabayashi, Masato; Shimizu, Yoichi; Yoshioka, Takeshi; Higashino, Kenichi; Numata, Yoshito; Okuda, Tomohiko; Zhao, Songji; Sakai, Shota; Igarashi, Yasuyuki; Kuge, Yuji.
Afiliación
  • Sugimoto M; Department of Integrated Molecular Imaging, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
  • Wakabayashi M; Shionogi Innovation Center for Drug Discovery, Discovery Research Laboratory for Innovative Frontier Medicines, Shionogi & Co., Ltd., Sapporo, Japan.
  • Shimizu Y; Shionogi Innovation Center for Drug Discovery, Discovery Research Laboratory for Innovative Frontier Medicines, Shionogi & Co., Ltd., Sapporo, Japan.
  • Yoshioka T; Central Institute of Isotope Science, Hokkaido University, Sapporo, Japan.
  • Higashino K; Laboratory of Bioanalysis and Molecular Imaging, Faculty of Pharmaceutical Science, Hokkaido University, Sapporo, Japan.
  • Numata Y; Shionogi Innovation Center for Drug Discovery, Discovery Research Laboratory for Innovative Frontier Medicines, Shionogi & Co., Ltd., Sapporo, Japan.
  • Okuda T; Shionogi Innovation Center for Drug Discovery, Discovery Research Laboratory for Innovative Frontier Medicines, Shionogi & Co., Ltd., Sapporo, Japan.
  • Zhao S; Shionogi Innovation Center for Drug Discovery, Discovery Research Laboratory for Innovative Frontier Medicines, Shionogi & Co., Ltd., Sapporo, Japan.
  • Sakai S; Drug Discovery Technologies, Discovery Research Laboratory for Core Therapeutic Areas, Shionogi & Co., Ltd., Toyonaka, Japan.
  • Igarashi Y; Department of Tracer Kinetics & Bioanalysis, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
  • Kuge Y; Department of Biomembrane and Biofunctional Chemistry, Faculty of Advanced Life Science, Hokkaido University, Sapporo, Japan.
PLoS One ; 11(3): e0152191, 2016.
Article en En | MEDLINE | ID: mdl-27010944
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esfingolípidos / Transferasas (Grupos de Otros Fosfatos Sustitutos) / Riñón / Obesidad Límite: Animals / Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2016 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esfingolípidos / Transferasas (Grupos de Otros Fosfatos Sustitutos) / Riñón / Obesidad Límite: Animals / Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2016 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos