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Tunnelling of thoracic epidural catheters is associated with fewer catheter-related infections: a retrospective registry analysis.
Bomberg, H; Kubulus, C; Herberger, S; Wagenpfeil, S; Kessler, P; Steinfeldt, T; Standl, T; Gottschalk, A; Stork, J; Meissner, W; Birnbaum, J; Koch, T; Sessler, D I; Volk, T; Raddatz, A.
Afiliación
  • Bomberg H; Department of Anaesthesiology, Intensive Care Medicine and Pain Medicine.
  • Kubulus C; Department of Anaesthesiology, Intensive Care Medicine and Pain Medicine.
  • Herberger S; Department of Anaesthesiology, Intensive Care Medicine and Pain Medicine.
  • Wagenpfeil S; Institute for Medical Biometry, Epidemiology and Medical Informatics, Saarland University, University Medical Centre, Homburg/Saar, Germany.
  • Kessler P; Department of Anaesthesiology, Intensive Care and Pain Medicine, Orthopaedic University Hospital, Frankfurt, Germany.
  • Steinfeldt T; Department of Anaesthesiology and Intensive Care Therapy, Philipps University Marburg, Marburg, Germany.
  • Standl T; Department of Anaesthesia, Intensive and Palliative Care Medicine, Academic Hospital Solingen, Solingen, Germany.
  • Gottschalk A; Department of Anaesthesiology, Intensive Care and Pain Medicine, Friederikenstift Hannover, Hannover, Germany.
  • Stork J; Centre for Anaesthesiology and Intensive Care Medicine, University Medical Centre Hamburg-Eppendorf, Martinistrasse 52, Hamburg D-20246, Germany.
  • Meissner W; Department of Anaesthesiology and Intensive Care, Jena University Hospital, Jena, Germany.
  • Birnbaum J; Department of Anaesthesiology and Operative Intensive Care Medicine, Charité Campus Virchow Klinikum and Campus Mitte, Charité University Medicine Berlin, Berlin, Germany.
  • Koch T; Department of Anesthesiology and Critical Care Medicine, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
  • Sessler DI; Department of Outcomes Research, Anesthesiology Institute, Cleveland Clinic, 9500 Euclid Avenue P77, Cleveland, OH 44195, USA.
  • Volk T; Department of Anaesthesiology, Intensive Care Medicine and Pain Medicine.
  • Raddatz A; Department of Anaesthesiology, Intensive Care Medicine and Pain Medicine.
Br J Anaesth ; 116(4): 546-53, 2016 Apr.
Article en En | MEDLINE | ID: mdl-26994232
BACKGROUND: Catheter-related infections are a serious complication of continuous thoracic epidural analgesia. Tunnelling catheters subcutaneously may reduce infection risk. We thus tested the hypothesis that tunnelling of thoracic epidural catheters is associated with a lower risk of catheter-related infections. METHODS: Twenty-two thousand, four hundred and eleven surgical patients with continuous thoracic epidural analgesia included in the German Network for Regional Anaesthesia registry between 2007 and 2014 were grouped by whether their catheters were tunnelled (n=12 870) or not (n=9541). Catheter-related infections in each group were compared with Student's unpaired t and χ(2) tests. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated with logistic regression, adjusting for potential confounding factors, including age, ASA physical status score, use of catheter for ≥4 days, multiple skin puncture, hospital, and surgical department. RESULTS: There were fewer catheter-related infections in patients with tunnelled catheters (4.5 vs 5.5%, P<0.001). Mild infections were also less common (4.0 vs 4.6%, P=0.009), as were moderate infections (0.4 vs 0.8%, P<0.001). After adjustment for potential confounding factors, tunnelling remained an independent prevention for any grade of infection (adjusted OR 0.51, 95% CI 0.42-0.61, P<0.001) and for mild infections (adjusted OR 0.54, 95% CI 0.43-0.66, P<0.001) and moderate and severe infections (adjusted OR 0.44, 95% CI 0.28-0.70, P=0.001). CONCLUSION: Tunnelling was associated with a lower risk of thoracic epidural catheter-related infections.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cateterismo / Analgesia Epidural / Espacio Epidural / Infecciones Relacionadas con Catéteres Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Br J Anaesth Año: 2016 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cateterismo / Analgesia Epidural / Espacio Epidural / Infecciones Relacionadas con Catéteres Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Br J Anaesth Año: 2016 Tipo del documento: Article Pais de publicación: Reino Unido