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Investigation of serum vitamin D levels in Chinese infertile men.
Zhu, C-L; Xu, Q-F; Li, S-X; Wei, Y-C; Zhu, G-C; Yang, C; Shi, Y-C.
Afiliación
  • Zhu CL; Department of Nuclear Medicine, Suzhou Municipal Hospital, Suzhou Hospital Affiliated to Nanjing Medical University, Suzhou, Jiangsu, China.
  • Xu QF; Department of Clinical Laboratory, Suzhou Municipal Hospital, Suzhou Hospital Affiliated to Nanjing Medical University, Suzhou, Jiangsu, China.
  • Li SX; Department of Nuclear Medicine, Suzhou Municipal Hospital, Suzhou Hospital Affiliated to Nanjing Medical University, Suzhou, Jiangsu, China.
  • Wei YC; Department of Nuclear Medicine, Suzhou Municipal Hospital, Suzhou Hospital Affiliated to Nanjing Medical University, Suzhou, Jiangsu, China.
  • Zhu GC; Department of Nuclear Medicine, Suzhou Municipal Hospital, Suzhou Hospital Affiliated to Nanjing Medical University, Suzhou, Jiangsu, China.
  • Yang C; Department of Nuclear Medicine, Suzhou Municipal Hospital, Suzhou Hospital Affiliated to Nanjing Medical University, Suzhou, Jiangsu, China.
  • Shi YC; Center for Reproduction and Genetics, Suzhou Municipal Hospital, Suzhou Hospital Affiliated to Nanjing Medical University, Suzhou, Jiangsu, China.
Andrologia ; 48(10): 1261-1266, 2016 Dec.
Article en En | MEDLINE | ID: mdl-26992658
Recently, the question of whether vitamin D exerts an effect on the pathogenic process of infertility has become the centre of attention. There are some controversial conclusions on this issue. Based on previous studies, we sought to explore the difference of serum 25-hydroxyvitamin D3 , 1,25-dihydroxyvitamin D3 levels between infertile patients and fertile men, and to find the influence on semen quality. The analysis of serum 25-hydroxyvitamin D3 level showed no significant difference between infertile patients and fertile men. However, the levels of serum 1,25-dihydroxyvitamin D3 in oligospermia (P < 0.05), asthenospermia (P < 0.01), oligoasthenospermia (P < 0.05) and azoospermia (P < 0.01) patients were significantly lower than those in fertile men. Moreover, serum 1,25-dihydroxyvitamin D3 level was positively correlated with progressive motility and total sperm number in infertile patients. In addition, a positive correlation between serum prolactin and 1,25-dihydroxyvitamin D3 was observed in fertile men. Our results indicated that lower vitamin D could be a risk factor for poor semen quality in infertile men. The 1,25-dihydroxyvitamin D3 , as the biologically active form of vitamin D, may be more significant.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vitamina D / Calcifediol / Infertilidad Masculina Tipo de estudio: Risk_factors_studies Límite: Adult / Humans / Male Idioma: En Revista: Andrologia Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vitamina D / Calcifediol / Infertilidad Masculina Tipo de estudio: Risk_factors_studies Límite: Adult / Humans / Male Idioma: En Revista: Andrologia Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania