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Bcl-2/MDM2 Dual Inhibitors Based on Universal Pyramid-Like α-Helical Mimetics.
Wang, Ziqian; Song, Ting; Feng, Yingang; Guo, Zongwei; Fan, Yudan; Xu, Wenjie; Liu, Lu; Wang, Anhui; Zhang, Zhichao.
Afiliación
  • Wang Z; State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology , No. 158-89, Zhongshan Road, Dalian 116012, People's Republic of China.
  • Song T; School of Life Science and Technology, Dalian University of Technology , Dalian 116024, People's Republic of China.
  • Feng Y; Shandong Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences , Qingdao 266101, People's Republic of China.
  • Guo Z; School of Life Science and Technology, Dalian University of Technology , Dalian 116024, People's Republic of China.
  • Fan Y; School of Life Science and Technology, Dalian University of Technology , Dalian 116024, People's Republic of China.
  • Xu W; State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology , No. 158-89, Zhongshan Road, Dalian 116012, People's Republic of China.
  • Liu L; State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology , No. 158-89, Zhongshan Road, Dalian 116012, People's Republic of China.
  • Wang A; State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology , No. 158-89, Zhongshan Road, Dalian 116012, People's Republic of China.
  • Zhang Z; State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology , No. 158-89, Zhongshan Road, Dalian 116012, People's Republic of China.
J Med Chem ; 59(7): 3152-62, 2016 Apr 14.
Article en En | MEDLINE | ID: mdl-26982372
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Conformación Proteica / Proteína p53 Supresora de Tumor / Apoptosis / Proteínas Proto-Oncogénicas c-bcl-2 / Proteínas Proto-Oncogénicas c-mdm2 / Antineoplásicos Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Conformación Proteica / Proteína p53 Supresora de Tumor / Apoptosis / Proteínas Proto-Oncogénicas c-bcl-2 / Proteínas Proto-Oncogénicas c-mdm2 / Antineoplásicos Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos