Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption.

Bowman, Thomas A; O'Keeffe, Kayleigh R; D'Aquila, Theresa; Yan, Qing Wu; Griffin, John D; Killion, Elizabeth A; Salter, Deanna M; Mashek, Douglas G; Buhman, Kimberly K; Greenberg, Andrew S

Bowman, Thomas A; O'Keeffe, Kayleigh R; D'Aquila, Theresa; Yan, Qing Wu; Griffin, John D; Killion, Elizabeth A; Salter, Deanna M; Mashek, Douglas G; Buhman, Kimberly K; Greenberg, Andrew S.

Afiliación

Bowman TA; Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA. Electronic address: thomas.bowman@tufts.edu.
O'Keeffe KR; Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA. Electronic address: kokeeffe@live.unc.edu.
D'Aquila T; Department of Nutrition Science, Purdue University, West Lafayette, IN, USA. Electronic address: tdaquila@gmail.com.
Yan QW; Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA. Electronic address: qing-wu.yan@tufts.edu.
Griffin JD; Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA. Electronic address: john.griffin@tufts.edu.
Killion EA; Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA. Electronic address: elizabeth.killion@tufts.edu.
Salter DM; Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA. Electronic address: deanna.salter@tufts.edu.
Mashek DG; Department of Food Science and Nutrition, University of Minnesota, St. Paul, MN, USA. Electronic address: dmashek@umn.edu.
Buhman KK; Department of Nutrition Science, Purdue University, West Lafayette, IN, USA. Electronic address: kbuhman@purdue.edu.
Greenberg AS; Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA. Electronic address: andrew.greenberg@tufts.edu.

Mol Metab ; 5(3): 210-220, 2016 Mar.

Article en En | MEDLINE | ID: mdl-26977393

Palabras clave

ACSL; ACSL, long-chain acyl-CoA synthetase; ACSL5−/−, mice with global ablation of ACSL5; AUC, area under the curve; Acyl-CoA; Dietary fat absorption; ES, embryonic stem; FGF21; FGF21, fibroblast growth factor 21; ITT, insulin tolerance test; Intestine; Liver; NAFLD, non-alcoholic fatty liver disease; PGC1α, PPAR-gamma coactivator 1α; PPAR, peroxisome proliferator activated receptor; RER, respiratory exchange ratio; SDS, sodium dodecyl sulfate; SREBP1c, steroid response element binding protein-1c; T2DM, type2 diabetes; UCP1, uncoupling protein-1; VLDL, very low density lipoprotein

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Health_economic_evaluation / Prognostic_studies Idioma: En Revista: Mol Metab Año: 2016 Tipo del documento: Article Pais de publicación: Alemania

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