Using Big Data to Evaluate the Association between Periodontal Disease and Rheumatoid Arthritis.
AMIA Annu Symp Proc
; 2015: 589-93, 2015.
Article
en En
| MEDLINE
| ID: mdl-26958193
An association between periodontal disease and rheumatoid arthritis is believed to exist. Most investigations into a possible relationship have been case-control studies with relatively low sample sizes. The advent of very large clinical repositories has created new opportunities for data-driven research. We conducted a retrospective cohort study to measure the association between periodontal disease and rheumatoid arthritis in a population of 25 million patients. We demonstrated that subjects with periodontal disease were roughly 1.4 times more likely to have rheumatoid arthritis. These results compare favorably with those of previous studies on smaller cohorts. Additional work is needed to identify the mechanisms behind this association and to determine if aggressive treatment of periodontal disease can alter the course of rheumatoid arthritis.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades Periodontales
/
Artritis Reumatoide
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
AMIA Annu Symp Proc
Asunto de la revista:
INFORMATICA MEDICA
Año:
2015
Tipo del documento:
Article
Pais de publicación:
Estados Unidos