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Using Big Data to Evaluate the Association between Periodontal Disease and Rheumatoid Arthritis.
Grasso, Michael A; Comer, Angela C; DiRenzo, Dana D; Yesha, Yelena; Rishe, Naphtali D.
Afiliación
  • Grasso MA; University of Maryland School of Medicine, Baltimore, Maryland.
  • Comer AC; University of Maryland School of Medicine, Baltimore, Maryland.
  • DiRenzo DD; University of Maryland School of Medicine, Baltimore, Maryland.
  • Yesha Y; University of Maryland Baltimore County, Baltimore, Maryland.
  • Rishe ND; Florida International University and NOA Data Science Institute Inc, Miami, Florida.
AMIA Annu Symp Proc ; 2015: 589-93, 2015.
Article en En | MEDLINE | ID: mdl-26958193
An association between periodontal disease and rheumatoid arthritis is believed to exist. Most investigations into a possible relationship have been case-control studies with relatively low sample sizes. The advent of very large clinical repositories has created new opportunities for data-driven research. We conducted a retrospective cohort study to measure the association between periodontal disease and rheumatoid arthritis in a population of 25 million patients. We demonstrated that subjects with periodontal disease were roughly 1.4 times more likely to have rheumatoid arthritis. These results compare favorably with those of previous studies on smaller cohorts. Additional work is needed to identify the mechanisms behind this association and to determine if aggressive treatment of periodontal disease can alter the course of rheumatoid arthritis.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Periodontales / Artritis Reumatoide Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: AMIA Annu Symp Proc Asunto de la revista: INFORMATICA MEDICA Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Periodontales / Artritis Reumatoide Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: AMIA Annu Symp Proc Asunto de la revista: INFORMATICA MEDICA Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos