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Association of dementia in patients with benign paroxysmal positional vertigo.
Lo, M-H; Lin, C-L; Chuang, E; Chuang, T-Y; Kao, C-H.
Afiliación
  • Lo MH; Department of Physical Medicine and Rehabilitation, Veterans General Hospital Taipei and National Yang-Ming University, Taipei, Taiwan.
  • Lin CL; Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan.
  • Chuang E; College of Medicine, China Medical University, Taichung, Taiwan.
  • Chuang TY; Intended B.S. Molecular and Cell Biology, University of California, Berkeley, CA, USA.
  • Kao CH; Department of Physical Medicine and Rehabilitation, Veterans General Hospital Taipei and National Yang-Ming University, Taipei, Taiwan.
Acta Neurol Scand ; 135(2): 197-203, 2017 Feb.
Article en En | MEDLINE | ID: mdl-26932875
OBJECTIVE: We conducted a cohort study to investigate whether benign paroxysmal positional vertigo (BPPV) is correlated with an increased risk of dementia. METHODS: We established a case cohort comprising 7818 patients aged over 20 years who were diagnosed with BPPV from 2000 to 2010. In addition, we formed a control cohort by randomly selecting 31,272 people without BPPV and matched them with the BPPV patients according to gender, age, and index year. Cox proportional hazard regressions were performed to compute the hazard ratio (HR) of dementia after we adjusted for demographic characteristics and comorbidity. RESULTS: The prevalence of comorbidity was higher among patients with BPPV than among those without BPPV. In addition, patients with BPPV exhibited a 1.24-fold (95% confidence interval, CI 1.09-1.40; P < 0.001) higher risk of dementia than those without BPPV after we adjusted for age, gender, and comorbidity. An analysis stratified according to demographic factors revealed that women with BPPV exhibited a 1.36-fold (95% CI 1.16-1.59; P < 0.001) higher risk of dementia. Patients with BPPV aged over 65 years exhibited a significantly higher risk of dementia (adjusted HR: 1.26; 95% CI 1.10-1.43; P < 0.001) than those without BPPV. CONCLUSIONS: Patients with BPPV exhibited a higher risk of dementia than those without BPPV.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Demencia / Vértigo Posicional Paroxístico Benigno Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Neurol Scand Año: 2017 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Dinamarca
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Demencia / Vértigo Posicional Paroxístico Benigno Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Neurol Scand Año: 2017 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Dinamarca