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Mycobacterium tuberculosis: Manipulator of Protective Immunity.
Korb, Vanessa C; Chuturgoon, Anil A; Moodley, Devapregasan.
Afiliación
  • Korb VC; Discipline of Medical Biochemistry and Chemical Pathology, University of KwaZulu-Natal, Howard College Campus, King George V Avenue, 4001 Durban, South Africa. vanessakorb@gmail.com.
  • Chuturgoon AA; Discipline of Medical Biochemistry and Chemical Pathology, University of KwaZulu-Natal, Howard College Campus, King George V Avenue, 4001 Durban, South Africa. chutur@ukzn.ac.za.
  • Moodley D; Discipline of Medical Biochemistry and Chemical Pathology, University of KwaZulu-Natal, Howard College Campus, King George V Avenue, 4001 Durban, South Africa. Devan_Moodley@hms.harvard.edu.
Int J Mol Sci ; 17(3): 131, 2016 Feb 25.
Article en En | MEDLINE | ID: mdl-26927066
Mycobacterium tuberculosis (MTB) is one of the most successful pathogens in human history and remains a global health challenge. MTB has evolved a plethora of strategies to evade the immune response sufficiently to survive within the macrophage in a bacterial-immunological equilibrium, yet causes sufficient immunopathology to facilitate its transmission. This review highlights MTB as the driver of disease pathogenesis and presents evidence of the mechanisms by which MTB manipulates the protective immune response into a pathological productive infection.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculoma / Evasión Inmune / Mycobacterium tuberculosis Límite: Animals / Humans Idioma: En Revista: Int J Mol Sci Año: 2016 Tipo del documento: Article País de afiliación: Sudáfrica Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculoma / Evasión Inmune / Mycobacterium tuberculosis Límite: Animals / Humans Idioma: En Revista: Int J Mol Sci Año: 2016 Tipo del documento: Article País de afiliación: Sudáfrica Pais de publicación: Suiza