Regulation of SIRT1 in aging: Roles in mitochondrial function and biogenesis.

Yuan, Yujia; Cruzat, Vinicius Fernandes; Newsholme, Philip; Cheng, Jingqiu; Chen, Younan; Lu, Yanrong

Yuan, Yujia; Cruzat, Vinicius Fernandes; Newsholme, Philip; Cheng, Jingqiu; Chen, Younan; Lu, Yanrong.

Afiliación

Yuan Y; Key Laboratory of Transplant Engineering and Immunology, NHFPC, Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, PR China.
Cruzat VF; School of Biomedical Sciences, CHIRI Biosciences, Curtin University, GPO Box U1987, Perth, Western Australia, Australia; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, Brazil.
Newsholme P; School of Biomedical Sciences, CHIRI Biosciences, Curtin University, GPO Box U1987, Perth, Western Australia, Australia.
Cheng J; Key Laboratory of Transplant Engineering and Immunology, NHFPC, Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, PR China.
Chen Y; Key Laboratory of Transplant Engineering and Immunology, NHFPC, Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, PR China; School of Biomedical Sciences, CHIRI Biosciences, Curtin University, GPO Box U1987, Perth, Western Australia, Australia. Electronic addre
Lu Y; Key Laboratory of Transplant Engineering and Immunology, NHFPC, Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, PR China. Electronic address: luyanrong@scu.edu.cn.

Mech Ageing Dev ; 155: 10-21, 2016 Apr.

Article en En | MEDLINE | ID: mdl-26923269

Asunto(s)

Envejecimiento/metabolismo; Mitocondrias/metabolismo; Dinámicas Mitocondriales; Sirtuina 1/metabolismo; Envejecimiento/genética; Animales; Senescencia Celular/genética; Humanos; Subunidad alfa del Factor 1 Inducible por Hipoxia/genética; Subunidad alfa del Factor 1 Inducible por Hipoxia/metabolismo; Mitocondrias/genética; Coactivador 1-alfa del Receptor Activado por Proliferadores de Peroxisomas gamma/genética; Coactivador 1-alfa del Receptor Activado por Proliferadores de Peroxisomas gamma/metabolismo; Sirtuina 1/genética

Palabras clave

HIF-1α; Oxidative phosphorylation; PGC-1α; Reactive oxygen species

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Envejecimiento / Sirtuina 1 / Dinámicas Mitocondriales / Mitocondrias Límite: Animals / Humans Idioma: En Revista: Mech Ageing Dev Año: 2016 Tipo del documento: Article Pais de publicación: Irlanda

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