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Drug design from the cryptic inhibitor envelope.
Lee, Chul-Jin; Liang, Xiaofei; Wu, Qinglin; Najeeb, Javaria; Zhao, Jinshi; Gopalaswamy, Ramesh; Titecat, Marie; Sebbane, Florent; Lemaitre, Nadine; Toone, Eric J; Zhou, Pei.
Afiliación
  • Lee CJ; Department of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.
  • Liang X; Department of Chemistry, Duke University, Durham, North Carolina 27708, USA.
  • Wu Q; Department of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.
  • Najeeb J; Department of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.
  • Zhao J; Department of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.
  • Gopalaswamy R; Department of Chemistry, Duke University, Durham, North Carolina 27708, USA.
  • Titecat M; Inserm, Univ. Lille, CHU Lille, Institut Pasteur de Lille, CNRS, U1019-UMR 8204-CIIL-Center for Infection and Immunity of Lille, F-59000 Lille, France.
  • Sebbane F; Inserm, Univ. Lille, CHU Lille, Institut Pasteur de Lille, CNRS, U1019-UMR 8204-CIIL-Center for Infection and Immunity of Lille, F-59000 Lille, France.
  • Lemaitre N; Inserm, Univ. Lille, CHU Lille, Institut Pasteur de Lille, CNRS, U1019-UMR 8204-CIIL-Center for Infection and Immunity of Lille, F-59000 Lille, France.
  • Toone EJ; Department of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.
  • Zhou P; Department of Chemistry, Duke University, Durham, North Carolina 27708, USA.
Nat Commun ; 7: 10638, 2016 Feb 25.
Article en En | MEDLINE | ID: mdl-26912110
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Inhibidores Enzimáticos / Escherichia coli / Amidohidrolasas / Antibacterianos Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Inhibidores Enzimáticos / Escherichia coli / Amidohidrolasas / Antibacterianos Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido