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Do Women With Anxiety or Depression Have Higher Rates of Myocardial Ischemia During Exercise Testing Than Men?
Paine, Nicola J; Bacon, Simon L; Pelletier, Roxanne; Arsenault, André; Diodati, Jean G; Lavoie, Kim L.
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  • Paine NJ; From the Department of Exercise Science, Concordia University, Montréal, Quebec, Canada (N.J.P., S.L.B.); Montréal Behavioural Medicine Centre, Hôpital du Sacré-Coeur à Montréal, Montréal, Quebec, Canada (N.J.P., S.L.B., A.A., K.L.L.); Department of Psychology, University of Quebec at Montreal, Mont
  • Bacon SL; From the Department of Exercise Science, Concordia University, Montréal, Quebec, Canada (N.J.P., S.L.B.); Montréal Behavioural Medicine Centre, Hôpital du Sacré-Coeur à Montréal, Montréal, Quebec, Canada (N.J.P., S.L.B., A.A., K.L.L.); Department of Psychology, University of Quebec at Montreal, Mont
  • Pelletier R; From the Department of Exercise Science, Concordia University, Montréal, Quebec, Canada (N.J.P., S.L.B.); Montréal Behavioural Medicine Centre, Hôpital du Sacré-Coeur à Montréal, Montréal, Quebec, Canada (N.J.P., S.L.B., A.A., K.L.L.); Department of Psychology, University of Quebec at Montreal, Mont
  • Arsenault A; From the Department of Exercise Science, Concordia University, Montréal, Quebec, Canada (N.J.P., S.L.B.); Montréal Behavioural Medicine Centre, Hôpital du Sacré-Coeur à Montréal, Montréal, Quebec, Canada (N.J.P., S.L.B., A.A., K.L.L.); Department of Psychology, University of Quebec at Montreal, Mont
  • Diodati JG; From the Department of Exercise Science, Concordia University, Montréal, Quebec, Canada (N.J.P., S.L.B.); Montréal Behavioural Medicine Centre, Hôpital du Sacré-Coeur à Montréal, Montréal, Quebec, Canada (N.J.P., S.L.B., A.A., K.L.L.); Department of Psychology, University of Quebec at Montreal, Mont
  • Lavoie KL; From the Department of Exercise Science, Concordia University, Montréal, Quebec, Canada (N.J.P., S.L.B.); Montréal Behavioural Medicine Centre, Hôpital du Sacré-Coeur à Montréal, Montréal, Quebec, Canada (N.J.P., S.L.B., A.A., K.L.L.); Department of Psychology, University of Quebec at Montreal, Mont
Circ Cardiovasc Qual Outcomes ; 9(2 Suppl 1): S53-61, 2016 Feb.
Article en En | MEDLINE | ID: mdl-26908861
BACKGROUND: Women diagnosed with coronary artery disease (CAD) typically experience worse outcomes relative to men, possibly through diagnosis and treatment delays. Reasons for these delays may be influenced by mood and anxiety disorders, which are more prevalent in women and have symptoms (eg, palpitations and fatigue) that may be confounded with CAD. Our study examined sex differences in the association between mood and anxiety disorders and myocardial ischemia in patients with and without a CAD history presenting for exercise stress tests. METHODS AND RESULTS: A total of 2342 patients (women n=760) completed a single photon emission computed tomographic exercise stress test (standard Bruce Protocol) and underwent a psychiatric interview (The Primary Care Evaluation of Mental Disorders) to assess mood and anxiety disorders. Ischemia was assessed using single photon emission computed tomography, with odds ratio used to calculate the effect of sex and mood/anxiety on the presence of ischemia during stress testing by CAD history in a stratified analyses, adjusted for relevant covariates. There was a sex by anxiety interaction with ischemia in those without a CAD history (P=0.015): women with anxiety were more likely to exhibit ischemia during exercise than women without anxiety (odds ratio, 1.75; 95% confidence interval, 1.05-2.89). No significant effects were observed for men nor mood. CONCLUSIONS: Women with anxiety and no CAD history had higher rates of ischemia than women without anxiety. Results suggest that anxiety symptoms, many of which overlap with those of CAD, might mask CAD symptoms among women (but not men) and contribute to referral and diagnostic delays. Further research is needed to confirm this hypothesis.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ansiedad / Isquemia Miocárdica / Depresión / Prueba de Esfuerzo Tipo de estudio: Clinical_trials / Guideline / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Circ Cardiovasc Qual Outcomes Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ansiedad / Isquemia Miocárdica / Depresión / Prueba de Esfuerzo Tipo de estudio: Clinical_trials / Guideline / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Circ Cardiovasc Qual Outcomes Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos