Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by G&#945;o and R7-binding Protein.

Tayou, Junior; Wang, Qiang; Jang, Geeng-Fu; Pronin, Alexey N; Orlandi, Cesare; Martemyanov, Kirill A; Crabb, John W; Slepak, Vladlen Z

Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by Gαo and R7-binding Protein.

Tayou, Junior; Wang, Qiang; Jang, Geeng-Fu; Pronin, Alexey N; Orlandi, Cesare; Martemyanov, Kirill A; Crabb, John W; Slepak, Vladlen Z.

Afiliación

Tayou J; From the Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, Florida 33136.
Wang Q; From the Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, Florida 33136.
Jang GF; the Cole Eye Institute Cleveland Clinic, Cleveland, Ohio 44195, and.
Pronin AN; From the Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, Florida 33136.
Orlandi C; the Department of Neuroscience, Scripps Research Institute, Jupiter, Florida 33458.
Martemyanov KA; the Department of Neuroscience, Scripps Research Institute, Jupiter, Florida 33458.
Crabb JW; the Cole Eye Institute Cleveland Clinic, Cleveland, Ohio 44195, and.
Slepak VZ; From the Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, Florida 33136, VSlepak@med.miami.edu.

J Biol Chem ; 291(17): 9133-47, 2016 Apr 22.

Article en En | MEDLINE | ID: mdl-26895961

Asunto(s)

Proteínas Portadoras/metabolismo; Subunidades alfa de la Proteína de Unión al GTP Gi-Go/metabolismo; Multimerización de Proteína/fisiología; Proteínas RGS/metabolismo; Animales; Proteínas Portadoras/genética; Subunidades alfa de la Proteína de Unión al GTP Gi-Go/genética; Humanos; Péptidos y Proteínas de Señalización Intracelular; Ratones; Ratones Noqueados; Proteínas RGS/genética

Palabras clave

G protein; G protein-coupled receptor (GPCR); R7-binding protein (R7BP); immunoprecipitation; oligomer; protein cross-linking; regulator of G protein signaling (RGS); subcellular localization

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Portadoras / Subunidades alfa de la Proteína de Unión al GTP Gi-Go / Proteínas RGS / Multimerización de Proteína Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos

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