Your browser doesn't support javascript.
loading
Erythrocytes and their role as health indicator: Using structure in a patient-orientated precision medicine approach.
Pretorius, Etheresia; Olumuyiwa-Akeredolu, Oore-Ofe O; Mbotwe, Sthembile; Bester, Janette.
Afiliación
  • Pretorius E; Department of Physiology, University of Pretoria, South Africa. Electronic address: resia.pretorius@up.ac.za.
  • Olumuyiwa-Akeredolu OO; Department of Physiology, University of Pretoria, South Africa.
  • Mbotwe S; Department of Physiology, University of Pretoria, South Africa.
  • Bester J; Department of Physiology, University of Pretoria, South Africa.
Blood Rev ; 30(4): 263-74, 2016 07.
Article en En | MEDLINE | ID: mdl-26878812
The relevance of erythrocyte light microscopy analysis (a well-known haematological method) is under the spotlight, however there is a place for innovative electron microscopy, (together with biochemical markers) in a pathology laboratory. Inflammation is a key indicator of the health status and erythrocytes are extremely sensitive to oxidative stress or cytokine upregulation, which typically accompany systemic inflammation in most diseases. They are probably the most adaptable cells, and due to their short lifespan, may form a vital indicator of health, and could play a central part in tracking disease and treatment. As the NIH is proposing a precision medicine approach and because individualised medicine should form an essential part in diagnosis and treatment, biophysical combined with biochemical analysis of erythrocytes may be a novel method to track the inflammatory status before and after treatment. This will allow a fully individualised patient orientated precision medicine approach, where one-medication-regime-fits-all is no longer appropriate.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microscopía Electrónica / Biomarcadores / Eritrocitos / Medicina de Precisión Tipo de estudio: Prognostic_studies Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Blood Rev Asunto de la revista: HEMATOLOGIA Año: 2016 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microscopía Electrónica / Biomarcadores / Eritrocitos / Medicina de Precisión Tipo de estudio: Prognostic_studies Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Blood Rev Asunto de la revista: HEMATOLOGIA Año: 2016 Tipo del documento: Article Pais de publicación: Reino Unido