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Novel strategy for a bispecific antibody: induction of dual target internalization and degradation.
Lee, J M; Lee, S H; Hwang, J-W; Oh, S J; Kim, B; Jung, S; Shim, S-H; Lin, P W; Lee, S B; Cho, M-Y; Koh, Y J; Kim, S Y; Ahn, S; Lee, J; Kim, K-M; Cheong, K H; Choi, J; Kim, K-A.
Afiliación
  • Lee JM; Open Innovation Team, Samsung Bioepis Co., Ltd., Incheon, South Korea.
  • Lee SH; Samsung Biomedical Research Institute, Samsung Advanced Institute of Technology (SAIT), Gyeonggi-do, South Korea.
  • Hwang JW; Bioassay Group, Quality Evaluation Team, Samsung Bioepis Co., Ltd., Incheon, South Korea.
  • Oh SJ; Open Innovation Team, Samsung Bioepis Co., Ltd., Incheon, South Korea.
  • Kim B; Open Innovation Team, Samsung Bioepis Co., Ltd., Incheon, South Korea.
  • Jung S; Open Innovation Team, Samsung Bioepis Co., Ltd., Incheon, South Korea.
  • Shim SH; Samsung Biomedical Research Institute, Samsung Advanced Institute of Technology (SAIT), Gyeonggi-do, South Korea.
  • Lin PW; Cell Engineering Team, Samsung Bioepis Co., Ltd., Incheon, South Korea.
  • Lee SB; Cell Engineering Team, Samsung Bioepis Co., Ltd., Incheon, South Korea.
  • Cho MY; Samsung Advanced Institute of Technology (SAIT), Gyeonggi-do, South Korea.
  • Koh YJ; Samsung Advanced Institute of Technology (SAIT), Gyeonggi-do, South Korea.
  • Kim SY; Department of Medicine, Division of Hematology-Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
  • Ahn S; Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
  • Lee J; Department of Medicine, Division of Hematology-Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
  • Kim KM; Department of Medicine, Division of Hematology-Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
  • Cheong KH; Samsung Advanced Institute of Technology (SAIT), Gyeonggi-do, South Korea.
  • Choi J; Samsung Biomedical Research Institute, Samsung Advanced Institute of Technology (SAIT), Gyeonggi-do, South Korea.
  • Kim KA; Open Innovation Team, Samsung Bioepis Co., Ltd., Incheon, South Korea.
Oncogene ; 35(34): 4437-46, 2016 08 25.
Article en En | MEDLINE | ID: mdl-26853467
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Anticuerpos Biespecíficos / Receptor ErbB-2 / Proteínas Proto-Oncogénicas c-met / Receptores ErbB / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Corea del Sur Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Anticuerpos Biespecíficos / Receptor ErbB-2 / Proteínas Proto-Oncogénicas c-met / Receptores ErbB / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Corea del Sur Pais de publicación: Reino Unido