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Quality of life changes over time in patients with chronic obstructive pulmonary disease.
Jones, Gary L.
Afiliación
  • Jones GL; Division of Pulmonary and Critical Care Medicine, University of Texas Southwestern at Dallas, Dallas, Texas.
Curr Opin Pulm Med ; 22(2): 125-9, 2016 Mar.
Article en En | MEDLINE | ID: mdl-26814143
PURPOSE OF REVIEW: Chronic obstructive pulmonary disease (COPD) is often considered to be a disease in which an inevitable decline in lung function results in increasing dyspnea and deteriorating quality of life. This review summarizes recent data that calls this classic paradigm into question. Studies evaluating the effects of chronic sputum production, physical activity, and inhaled medications on quality of life and prognosis are also discussed. RECENT FINDINGS: Chronic sputum production and level of dyspnea contribute at least as much to impairment of quality of life and prognosis as does abnormal lung function. An accelerated decline in FEV1 occurs in only half of the patients who develop COPD. Current pharmacotherapy has been shown to moderate disease progression and quality of life, although the effects are lost when inhaled corticosteroids are discontinued. Declining physical activity begins early in the course of COPD, but increasing activity levels result in improved quality of life and a slower decline in lung function. SUMMARY: Symptoms and activity levels are as important as measuring FEV1 in determining disease severity, quality of life, and prognosis of COPD. Therapies exist that moderate the course of the disease, and small sustained increases in physical activity may slow physical deterioration and improve health-related quality of life.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad Pulmonar Obstructiva Crónica Tipo de estudio: Diagnostic_studies / Prognostic_studies Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Curr Opin Pulm Med Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad Pulmonar Obstructiva Crónica Tipo de estudio: Diagnostic_studies / Prognostic_studies Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Curr Opin Pulm Med Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos