Nauclea officinalis inhibits inflammation in LPS-mediated RAW 264.7 macrophages by suppressing the NF-&#954;B signaling pathway.

Zhai, Xiao-Ting; Zhang, Zhi-Yuan; Jiang, Cui-Hua; Chen, Jia-Quan; Ye, Ji-Qing; Jia, Xiao-Bin; Yang, Yi; Ni, Qian; Wang, Shu-Xia; Song, Jie; Zhu, Fen-Xia

Nauclea officinalis inhibits inflammation in LPS-mediated RAW 264.7 macrophages by suppressing the NF-κB signaling pathway.

Zhai, Xiao-Ting; Zhang, Zhi-Yuan; Jiang, Cui-Hua; Chen, Jia-Quan; Ye, Ji-Qing; Jia, Xiao-Bin; Yang, Yi; Ni, Qian; Wang, Shu-Xia; Song, Jie; Zhu, Fen-Xia.

Afiliación

Zhai XT; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, PR China; Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing 210028, PR China; Department of Analytical Chemistry, China Pharmaceutical University, Nanji
Zhang ZY; College of Pharmacy, Hainan Medical University, Haikou 570102, PR China.
Jiang CH; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, PR China; Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing 210028, PR China.
Chen JQ; Department of Analytical Chemistry, China Pharmaceutical University, Nanjing 210009, PR China.
Ye JQ; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, PR China.
Jia XB; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, PR China; Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing 210028, PR China.
Yang Y; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, PR China; Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing 210028, PR China.
Ni Q; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, PR China; Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing 210028, PR China.
Wang SX; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, PR China; Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing 210028, PR China.
Song J; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, PR China; Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing 210028, PR China.
Zhu FX; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, PR China; Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing 210028, PR China. Electronic address: zfxcjq@126.com.

J Ethnopharmacol ; 183: 159-165, 2016 May 13.

Article en En | MEDLINE | ID: mdl-26806575

Asunto(s)

Inflamación/inducido químicamente; Inflamación/tratamiento farmacológico; Lipopolisacáridos/farmacología; Macrófagos/efectos de los fármacos; FN-kappa B/metabolismo; Rubiaceae/química; Transducción de Señal/efectos de los fármacos; Animales; Antiinflamatorios/química; Antiinflamatorios/farmacología; Células Cultivadas; Inflamación/metabolismo; Mediadores de Inflamación/metabolismo; Interleucina-1beta/metabolismo; Interleucina-6/metabolismo; Macrófagos/metabolismo; Ratones; Óxido Nítrico Sintasa de Tipo II/metabolismo; Óxidos de Nitrógeno/metabolismo; Fitoterapia/métodos; Extractos Vegetales/química; Extractos Vegetales/farmacología; Factor de Transcripción ReIA/metabolismo; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide; 3-epi-pumiloside (CAS no: 126722-26-7); Acetonitrile (PubChem CID: 6342); Anti-inflammation; DMSO (PubChem CID: 679); EtOH (PubChem CID: 702); Methanoic acid (PubChem CID: 284); NF-κB; NaNO(2) (PubChem CID: 23668193); Nauclea officinalis; Pro-inflammatory cytokines; Pumiloside (PubChem CID: 10346314); Strictosamide (PubChem CID: 11969629); Vincosamide (PubChem CID: 44567197)

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Lipopolisacáridos / FN-kappa B / Rubiaceae / Inflamación / Macrófagos Límite: Animals Idioma: En Revista: J Ethnopharmacol Año: 2016 Tipo del documento: Article Pais de publicación: Irlanda

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google