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Simultaneous determination of gefitinib and its major metabolites in mouse plasma by HPLC-MS/MS and its application to a pharmacokinetics study.
Zheng, Nan; Zhao, Can; He, Xi-Ran; Jiang, Shan-Tong; Han, Shu-Yan; Xu, Guo-Bing; Li, Ping-Ping.
Afiliación
  • Zheng N; Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing 100142, PR China; National Drug Clinical Trial Center, Peking University Cancer Hospital & Institute, Beijing 100142, PR China.
  • Zhao C; Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing 100142, PR China; Department of Integration of Chinese and Western Medicine, Peking University Cancer Hospital & Institute, Beijing 100142, PR China.
  • He XR; Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing 100142, PR China; Department of Integration of Chinese and Western Medicine, Peking University Cancer Hospital & Institute, Beijing 100142, PR China.
  • Jiang ST; Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing 100142, PR China; Department of Integration of Chinese and Western Medicine, Peking University Cancer Hospital & Institute, Beijing 100142, PR China.
  • Han SY; Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing 100142, PR China; Department of Integration of Chinese and Western Medicine, Peking University Cancer Hospital & Institute, Beijing 100142, PR China. Electronic address: shuyanhan@bjmu.edu.cn.
  • Xu GB; Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing 100142, PR China; National Drug Clinical Trial Center, Peking University Cancer Hospital & Institute, Beijing 100142, PR China.
  • Li PP; Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing 100142, PR China; Department of Integration of Chinese and Western Medicine, Peking University Cancer Hospital & Institute, Beijing 100142, PR China. Electronic address: lppma123@sina.com.
J Chromatogr B Analyt Technol Biomed Life Sci ; 1011: 215-22, 2016 Feb 01.
Article en En | MEDLINE | ID: mdl-26795401
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quinazolinas / Cromatografía Líquida de Alta Presión / Espectrometría de Masas en Tándem Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Asunto de la revista: ENGENHARIA BIOMEDICA Año: 2016 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quinazolinas / Cromatografía Líquida de Alta Presión / Espectrometría de Masas en Tándem Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Asunto de la revista: ENGENHARIA BIOMEDICA Año: 2016 Tipo del documento: Article Pais de publicación: Países Bajos