Exploiting the CRISPR/Cas9 PAM Constraint for Single-Nucleotide Resolution Interventions.

Li, Yi; Mendiratta, Saurabh; Ehrhardt, Kristina; Kashyap, Neha; White, Michael A; Bleris, Leonidas

Li, Yi; Mendiratta, Saurabh; Ehrhardt, Kristina; Kashyap, Neha; White, Michael A; Bleris, Leonidas.

Afiliación

Li Y; Bioengineering Department, The University of Texas at Dallas, 800 West Campbell Road, Richardson, Texas 75080, United States of America.
Mendiratta S; Center for Systems Biology, The University of Texas at Dallas, 800 West Campbell Road, Richardson, Texas 75080, United States of America.
Ehrhardt K; Department of Cell Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, Texas 75390, United States of America.
Kashyap N; Bioengineering Department, The University of Texas at Dallas, 800 West Campbell Road, Richardson, Texas 75080, United States of America.
White MA; Center for Systems Biology, The University of Texas at Dallas, 800 West Campbell Road, Richardson, Texas 75080, United States of America.
Bleris L; Bioengineering Department, The University of Texas at Dallas, 800 West Campbell Road, Richardson, Texas 75080, United States of America.

PLoS One ; 11(1): e0144970, 2016.

Article en En | MEDLINE | ID: mdl-26788852

Asunto(s)

Sistemas CRISPR-Cas; Polimorfismo de Nucleótido Simple; Proteínas Proto-Oncogénicas p21(ras)/genética; ARN/química; Bencimidazoles/farmacología; Línea Celular Tumoral; Resistencia a Antineoplásicos; Células HEK293; Humanos; ARN/metabolismo; Edición de ARN; ARN Guía de Kinetoplastida/genética

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN / Proteínas Proto-Oncogénicas p21(ras) / Polimorfismo de Nucleótido Simple / Sistemas CRISPR-Cas Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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