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Treatment of Intravenous Leiomyomatosis with Cardiac Extension following Incomplete Resection.
Doyle, Mathew P; Li, Annette; Villanueva, Claudia I; Peeceeyen, Sheen C S; Cooper, Michael G; Hanel, Kevin C; Fermanis, Gary G; Robertson, Greg.
Afiliación
  • Doyle MP; Department of Cardiothoracic Surgery, St George Hospital, Sydney, NSW 2217, Australia; Graduate School of Medicine, University of Wollongong, Sydney, NSW 2252, Australia.
  • Li A; Department of Cardiothoracic Surgery, St George Hospital, Sydney, NSW 2217, Australia.
  • Villanueva CI; Department of Cardiothoracic Surgery, St George Hospital, Sydney, NSW 2217, Australia; University of New South Wales, Sydney, NSW 2000, Australia.
  • Peeceeyen SC; Department of Cardiothoracic Surgery, St George Hospital, Sydney, NSW 2217, Australia.
  • Cooper MG; Department of Anesthesia, St George Hospital, Sydney, NSW 2217, Australia.
  • Hanel KC; University of New South Wales, Sydney, NSW 2000, Australia; Department of Vascular Surgery, St George Hospital, Sydney, NSW 2217, Australia.
  • Fermanis GG; Department of Cardiothoracic Surgery, St George Hospital, Sydney, NSW 2217, Australia.
  • Robertson G; University of New South Wales, Sydney, NSW 2000, Australia; Department of Obstetrics & Gynecology, St George Hospital, Sydney, NSW 2217, Australia.
Int J Vasc Med ; 2015: 756141, 2015.
Article en En | MEDLINE | ID: mdl-26783463
Aim. Intravenous leiomyomatosis (IVL) with cardiac extension (CE) is a rare variant of benign uterine leiomyoma. Incomplete resection has a recurrence rate of over 30%. Different hormonal treatments have been described following incomplete resection; however no standard therapy currently exists. We review the literature for medical treatments options following incomplete resection of IVL with CE. Methods. Electronic databases were searched for all studies reporting IVL with CE. These studies were then searched for reports of patients with inoperable or incomplete resection and any further medical treatments. Our database was searched for patients with medical therapy following incomplete resection of IVL with CE and their results were included. Results. All studies were either case reports or case series. Five literature reviews confirm that surgery is the only treatment to achieve cure. The uses of progesterone, estrogen modulation, gonadotropin-releasing hormone antagonism, and aromatase inhibition have been described following incomplete resection. Currently no studies have reviewed the outcomes of these treatments. Conclusions. Complete surgical resection is the only means of cure for IVL with CE, while multiple hormonal therapies have been used with varying results following incomplete resection. Aromatase inhibitors are the only reported treatment to prevent tumor progression or recurrence in patients with incompletely resected IVL with CE.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Systematic_reviews Idioma: En Revista: Int J Vasc Med Año: 2015 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Systematic_reviews Idioma: En Revista: Int J Vasc Med Año: 2015 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Estados Unidos