Inhibition of WWP2 suppresses proliferation, and induces G1 cell cycle arrest and apoptosis in liver cancer cells.

Xu, Sheng-Qian; Qin, Yong; Pan, De-Biao; Ye, Guan-Xiong; Wu, Cheng-Jun; Wang, Shi; Jiang, Jin-Yan; Fu, Jing; Wang, Chao-Jun

Xu, Sheng-Qian; Qin, Yong; Pan, De-Biao; Ye, Guan-Xiong; Wu, Cheng-Jun; Wang, Shi; Jiang, Jin-Yan; Fu, Jing; Wang, Chao-Jun.

Afiliación

Xu SQ; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.
Qin Y; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.
Pan DB; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.
Ye GX; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.
Wu CJ; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.
Wang S; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.
Jiang JY; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.
Fu J; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.
Wang CJ; Department of Hepatobiliary Surgery, People's Hospital of Lishui, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang 323000, P.R. China.

Mol Med Rep ; 13(3): 2261-6, 2016 Mar.

Article en En | MEDLINE | ID: mdl-26783238

Asunto(s)

Apoptosis; Puntos de Control de la Fase G1 del Ciclo Celular; Neoplasias Hepáticas/patología; Ubiquitina-Proteína Ligasas/metabolismo; Adulto; Anciano; Anciano de 80 o más Años; Apoptosis/genética; Biomarcadores de Tumor/metabolismo; Western Blotting; Línea Celular Tumoral; Proliferación Celular; Supervivencia Celular/genética; Femenino; Puntos de Control de la Fase G1 del Ciclo Celular/genética; Regulación Neoplásica de la Expresión Génica; Técnicas de Silenciamiento del Gen; Humanos; Neoplasias Hepáticas/genética; Masculino; Persona de Mediana Edad; ARN Mensajero/genética; ARN Mensajero/metabolismo; Transducción de Señal/genética; Ubiquitina-Proteína Ligasas/genética; Regulación hacia Arriba/genética

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Apoptosis / Ubiquitina-Proteína Ligasas / Puntos de Control de la Fase G1 del Ciclo Celular / Neoplasias Hepáticas Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Mol Med Rep Año: 2016 Tipo del documento: Article Pais de publicación: Grecia

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