Novel renin inhibitors containing derivatives of N-alkylleucyl-ß-hydroxy-Î³-amino acids.

Winiecka, Iwona; Jaworski, Pawel; Mazurek, Aleksander Pawel; Marszalek, Dorota; Goldnik, Anna; Sokulski, Daniel

Winiecka, Iwona; Jaworski, Pawel; Mazurek, Aleksander Pawel; Marszalek, Dorota; Goldnik, Anna; Sokulski, Daniel.

Afiliación

Winiecka I; Department of Drug Chemistry, Medical University of Warsaw, Banacha 1, 02 - 097, Warsaw, Poland.
Jaworski P; Department of Drug Chemistry, Medical University of Warsaw, Banacha 1, 02 - 097, Warsaw, Poland.
Mazurek AP; Department of Drug Chemistry, Medical University of Warsaw, Banacha 1, 02 - 097, Warsaw, Poland.
Marszalek D; Department of Drug Chemistry, Medical University of Warsaw, Banacha 1, 02 - 097, Warsaw, Poland.
Goldnik A; Department of Drug Chemistry, Medical University of Warsaw, Banacha 1, 02 - 097, Warsaw, Poland.
Sokulski D; Department of Drug Chemistry, Medical University of Warsaw, Banacha 1, 02 - 097, Warsaw, Poland.

J Pept Sci ; 22(2): 106-15, 2016 Feb.

Article en En | MEDLINE | ID: mdl-26780837

Asunto(s)

Ácidos Grasos/química; Leucina/análogos & derivados; Leucina/química; Inhibidores de Proteasas/química; Renina/antagonistas & inhibidores; Angiotensinas/química; Humanos; Modelos Moleculares; Renina/química

Palabras clave

amino acids; hypertension treatment; pseudodipeptidic unit; renin inhibitors

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de Proteasas / Renina / Ácidos Grasos / Leucina Límite: Humans Idioma: En Revista: J Pept Sci Asunto de la revista: BIOQUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Reino Unido

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