Analysis of possible food/nutrient and drug interactions in hospitalized patients.
Einstein (Sao Paulo)
; 8(3): 298-302, 2010 Sep.
Article
en En, Pt
| MEDLINE
| ID: mdl-26760143
OBJECTIVE: To evaluate the prescription in relation to the possible interactions between drugs and foods/nutrients in the diets of patients in the Hospital Regional Justino Luz in the municipality of Picos, Piauí, Brazil. METHODS: The sample consisted of 60 medical records of patients admitted at the hospital. The records were analyzed according to the presence or absence of interactions between drugs and foods/nutrients of the prescribed diets. RESULTS: Of the 82 drugs prescribed in all periods, there were 16 drugs (19.5%) with possible interaction with food, a total of 60 interactions between nutrient/food and medicine. Thus, 18 (30%), 10 (17%) and 8 (13%) possible interactions were identified with captopril (cardiovascular drug) with acetylsalicylic acid (anti-inflammatory) and spironolactone (diuretic), respectively representing the highest numbers of interactions among the classes of investigated drugs. It was also found that the total interactions between food/nutrients and drugs, 32 (53%) accounted for interactions with cardiovascular drugs, 13 (22%) with anti-inflammatory drugs, 11 (18%) with diuretic agents e 4 (7%) with drugs that act on the digestive tract. CONCLUSION: There was a high number of interactions between food/nutrients and medicines emphasizing the need for prior knowledge of these interactions as a way to avoid impairment in the treatment, longer hospital stays and/or damage to the nutritional status of the patients.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
/
Pt
Revista:
Einstein (Sao Paulo)
Año:
2010
Tipo del documento:
Article
Pais de publicación:
Brasil