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A new flavane acid from the fruits of Illicium verum.
Wu, Liang-Deng; Xiong, Chun-Lan; Chen, Zi-Zhan; He, Rui-Jie; Zhang, Yan-Jun; Huang, Yan; Deng, Sheng-Ping; Yang, Rui-Yun; Li, Jun.
Afiliación
  • Wu LD; a Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), School of Environment and Resource , Guangxi Normal University , Guilin , P. R. China.
  • Xiong CL; b Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Ministry of Education of China) , Guilin , P. R. China.
  • Chen ZZ; a Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), School of Environment and Resource , Guangxi Normal University , Guilin , P. R. China.
  • He RJ; b Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Ministry of Education of China) , Guilin , P. R. China.
  • Zhang YJ; a Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), School of Environment and Resource , Guangxi Normal University , Guilin , P. R. China.
  • Huang Y; b Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Ministry of Education of China) , Guilin , P. R. China.
  • Deng SP; a Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), School of Environment and Resource , Guangxi Normal University , Guilin , P. R. China.
  • Yang RY; b Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection (Ministry of Education of China) , Guilin , P. R. China.
  • Li J; a Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), School of Environment and Resource , Guangxi Normal University , Guilin , P. R. China.
Nat Prod Res ; 30(14): 1585-90, 2016 Jul.
Article en En | MEDLINE | ID: mdl-26734839
A new compound, illiciumflavane acid (1), along with 13 known compounds (2-14), were isolated from the fruits of Illicium verum Hook. F. Their structures were elucidated through various spectroscopic methods, including 1D NMR ((1)H NMR, (13)C NMR), 2D NMR (HMQC, HMBC and NOESY) and HRMS. The stereochemistry at the chiral centres was determined using CD spectrum as well as analyses of coupling constants and optical rotation data. Cytotoxicity evaluation of four compounds showed that illiciumflavane acid and (E)-1,2-bis(4-methoxyphenyl)ethene exhibited potential against A549 activities with IC50 values of 4.63 µM and 9.17 µM, respectively.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Flavonoides / Illicium / Frutas Límite: Humans Idioma: En Revista: Nat Prod Res Año: 2016 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Flavonoides / Illicium / Frutas Límite: Humans Idioma: En Revista: Nat Prod Res Año: 2016 Tipo del documento: Article Pais de publicación: Reino Unido