Cerebral Vasomotor Reactivity and Apnea Test in Symptomatic and Asymptomatic High-Grade Carotid Stenosis.
Srp Arh Celok Lek
; 143(9-10): 520-4, 2015.
Article
en En
| MEDLINE
| ID: mdl-26727857
INTRODUCTION: Cerebral vasomotor reactivity (VMR) represents an autoregulatory response of the arterial trunks on the specific vasoactive stimuli, most commonly CO2. OBJECTIVE: The aim of this retrospective study was to compare VMR in high-grade symptomatic (SCAS) and asymptomatic carotid stenosis (ACAS), using the apnea test to evaluate the hemodynamic status. METHODS: The study included 50 patients who were hospitalized at the neurology and vascular surgery departments as part of preparation for carotid endarterectomy. We evaluated VMR by calculating the breath holding index (BHI) in 34 patients with SCAS and 16 patients with ACAS, with isolated high-grade carotid stenosis. We evaluated the impact of risk factors and collateral circulation on BHI, as well as the correlation between the degree of carotid stenosis and BHI. RESULTS: A pathological BHI was more frequent in the SCAS group (p<0.01). There was no difference in the range of BHI values between the groups, both ipsilaterally and contralaterally. Only male gender was associated with pathological BHI in both groups (p<0.05). Collateral circulation did not exist in over 60% of all subjects. We confirmed a negative correlation between the degree of carotid stenosis and BHI. CONCLUSION: SCAS and ACAS patients present with different hemodynamics. While ACAS patients have stable hemodynamics, combination of hemodynamic and thromboembolic effects is characteristic of SCAS patients.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Apnea
/
Circulación Cerebrovascular
/
Estenosis Carotídea
/
Hemodinámica
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Srp Arh Celok Lek
Año:
2015
Tipo del documento:
Article
Pais de publicación:
Serbia