Nicastrin is required for amyloid precursor protein (APP) but not Notch processing, while anterior pharynx-defective 1 is dispensable for processing of both APP and Notch.

Hu, Chen; Zeng, Linlin; Li, Ting; Meyer, Michael A; Cui, Mei-Zhen; Xu, Xuemin

Hu, Chen; Zeng, Linlin; Li, Ting; Meyer, Michael A; Cui, Mei-Zhen; Xu, Xuemin.

Afiliación

Hu C; Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee, USA.
Zeng L; School of Life Sciences, Jilin University, Changchun, China.
Li T; Department of Cell Biology, Tianjin Medical University, Tianjin, China.
Meyer MA; Sisters Hospital, Buffalo, New York, USA.
Cui MZ; Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee, USA.
Xu X; Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee, USA.

J Neurochem ; 136(6): 1246-1258, 2016 Mar.

Article en En | MEDLINE | ID: mdl-26717550

Palabras clave

APP; Alzheimer's disease; Aph-1; gamma-secretase; nicastrin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Neurochem Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

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