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Production and cross-sectional characterization of aligned co-electrospun hollow microfibrous bulk assemblies.
Zhou, Feng-Lei; Parker, Geoff J M; Eichhorn, Stephen J; Hubbard Cristinacce, Penny L.
Afiliación
  • Zhou FL; Centre for Imaging Sciences, The University of Manchester, Manchester M13 9PT, UK ; The School of Materials, The University of Manchester, Manchester M13 9PL, UK ; CRUK-EPSRC Cancer Imaging Centre in Cambridge and Manchester, UK.
  • Parker GJ; Centre for Imaging Sciences, The University of Manchester, Manchester M13 9PT, UK ; CRUK-EPSRC Cancer Imaging Centre in Cambridge and Manchester, UK.
  • Eichhorn SJ; College of Engineering, Mathematics and Physical Sciences, University of Exeter, Exeter EX4 4QF, UK.
  • Hubbard Cristinacce PL; Centre for Imaging Sciences, The University of Manchester, Manchester M13 9PT, UK ; School of Psychological Sciences, University of Manchester, Manchester M13 9PT, UK.
Mater Charact ; 109: 25-35, 2015 Nov.
Article en En | MEDLINE | ID: mdl-26702249
The development of co-electrospun (co-ES) hollow microfibrous assemblies of an appreciable thickness is critical for many practical applications, including filtration membranes and tissue-mimicking scaffolds. In this study, thick uniaxially aligned hollow microfibrous assemblies forming fiber bundles and strips were prepared by co-ES of polycaprolactone (PCL) and polyethylene oxide (PEO) as shell and core materials, respectively. Hollow microfiber bundles were deposited on a fixed rotating disc, which resulted in non-controllable cross-sectional shapes on a macroscopic scale. In comparison, fiber strips were produced with tuneable thickness and width by additionally employing an x-y translation stage in co-ES. Scanning electron microscopy (SEM) images of cross-sections of fiber assemblies were analyzed to investigate the effects of production time (from 0.5 h to 12 h), core flow rate (from 0.8 mL/h to 2.0 mL/h) and/or translation speed (from 0.2 mm/s to 5 mm/s) on the pores and porosity. We observed significant changes in pore size and shape with core flow rate but the influence of production time varied; five strips produced under the same conditions had reasonably good size and porosity reproducibility; pore sizes didn't vary significantly from strip bottom to surface, although the porosity gradually decreased and then returned to the initial level.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prevalence_studies Idioma: En Revista: Mater Charact Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prevalence_studies Idioma: En Revista: Mater Charact Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos