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Streptococcus pneumoniae as cause of infection in infants less than 60 days of age: serotypes and antimicrobial susceptibility.
Soto-Noguerón, Araceli; Carnalla-Barajas, María Noemí; Solórzano-Santos, Fortino; Arrendondo-García, José Luis; Arzate-Barbosa, Patricia; Tinoco-Favila, Juan Carlos; Anzurez-Gutiérrez, Azarell; Echániz-Aviles, Gabriela.
Afiliación
  • Soto-Noguerón A; Instituto Nacional de Salud Pública, Avenida Universidad 655, Cuernavaca, Morelos 62100, Mexico.
  • Carnalla-Barajas MN; Instituto Nacional de Salud Pública, Avenida Universidad 655, Cuernavaca, Morelos 62100, Mexico.
  • Solórzano-Santos F; Unidad Médica de Alta Especialidad, Hospital de Pediatría Centro Médico Nacional SXXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
  • Arrendondo-García JL; Instituto Nacional de Pediatría, Insurgentes Cuicuilco, Mexico City, Mexico.
  • Arzate-Barbosa P; Instituto Nacional de Pediatría, Insurgentes Cuicuilco, Mexico City, Mexico.
  • Tinoco-Favila JC; Hospital General de Durango, Durango, Mexico.
  • Anzurez-Gutiérrez A; Hospital General de León, Obregon, León, Guanajuato, Mexico.
  • Echániz-Aviles G; Instituto Nacional de Salud Pública, Avenida Universidad 655, Cuernavaca, Morelos 62100, Mexico. Electronic address: igechaniz@insp.mx.
Int J Infect Dis ; 42: 69-73, 2016 Jan.
Article en En | MEDLINE | ID: mdl-26673859
OBJECTIVE: The aim of this study was to determine the distribution of serotypes and the antimicrobial susceptibilities of Streptococcus pneumoniae clinical isolates causing invasive and non-invasive disease in children aged ≤60 days in hospitals in Mexico. METHODS: A 15-year retrospective study was conducted for the period 2000 to 2014. Pneumococcal clinical isolates were serotyped by Quellung reaction, and antimicrobial susceptibility testing was performed with the broth microdilution method. RESULTS: A total of 126 pneumococcal isolates were collected. Pneumonia was the most frequent diagnosis (40.5%), followed by meningitis (29.4%), septicemia (16.7%), and other clinical entities, including otitis media and conjunctivitis (13.5%). The most frequent serotypes before the introduction of heptavalent pneumococcal conjugate vaccine (PCV7) were 19F, 23F, 7F, and 35B. Serotypes 3, 6A, 10A, 12F, and 15A/B increased after the introduction of PCV7. Serotype 19A was isolated most frequently in the pneumonia and meningitis cases only after the introduction of PCV7, and it displayed a high resistance to penicillin. CONCLUSIONS: Although the number of infections in infants aged ≤60 days was low, such infections were not unusual events. New vaccination strategies should be evaluated to limit the risks in this age group.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Neumocócicas / Streptococcus pneumoniae Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Female / Humans / Infant / Male / Newborn Idioma: En Revista: Int J Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2016 Tipo del documento: Article País de afiliación: México Pais de publicación: Canadá
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Neumocócicas / Streptococcus pneumoniae Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Female / Humans / Infant / Male / Newborn Idioma: En Revista: Int J Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2016 Tipo del documento: Article País de afiliación: México Pais de publicación: Canadá