The evaluation of non-enzymatic antioxidants effects in limiting tumor- associated oxidative stress, in a tumor rat model.
J Med Life
; 8(4): 513-6, 2015.
Article
en En
| MEDLINE
| ID: mdl-26664481
Active oxygen species are produced as a consequence of normal aerobic metabolism. Of these, free radicals are usually metabolized or inactivated in vivo by a team of antioxidants. Individual members are a trained team fighting antioxidants to prevent the generation of ROS, destroy or oxidizing potential of capture. In terms of physiological oxidative stress, induced tissue attack is minimal. A relative or absolute deficiency in the antioxidant defense may lead to increased oxidative stress and this event is associated with both the causes and consequences of diseases and cancer, included here. The aim of the study is to identify the role of antioxidant defense systems and the reduction of oxidative stress in dynamic growth and development of malignant tumors. Our in vivo study was developed and referred to carcinosarcoma carriers Wistar rats treated with non-enzymatic antioxidants: vitamin C, vitamin A, zinc salt (II), and arginine in various combinations. Treatment was initiated three weeks before tumor induction.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Estrés Oxidativo
/
Neoplasias
/
Antioxidantes
Tipo de estudio:
Risk_factors_studies
Límite:
Animals
Idioma:
En
Revista:
J Med Life
Asunto de la revista:
MEDICINA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Rumanía
Pais de publicación:
Rumanía