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Switching treatments in COPD: implications for costs and treatment adherence.
Braido, Fulvio; Lavorini, Federico; Blasi, Francesco; Baiardini, Ilaria; Canonica, Giorgio Walter.
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  • Braido F; Respiratory and Allergy Diseases Clinic, Department of Internal Medicine, University of Genoa, IRCCS AOU San Martino-IST, Genoa, Italy.
  • Lavorini F; Department of Experimental and Clinical Medicine, Careggi University Hospital, Florence, Italy.
  • Blasi F; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, IRCCS Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
  • Baiardini I; Respiratory and Allergy Diseases Clinic, Department of Internal Medicine, University of Genoa, IRCCS AOU San Martino-IST, Genoa, Italy.
  • Canonica GW; Respiratory and Allergy Diseases Clinic, Department of Internal Medicine, University of Genoa, IRCCS AOU San Martino-IST, Genoa, Italy.
Int J Chron Obstruct Pulmon Dis ; 10: 2601-8, 2015.
Article en En | MEDLINE | ID: mdl-26664108
Inhaled therapy is key to the management of chronic obstructive pulmonary disease (COPD). New drugs and inhalers have recently been launched or will soon become available, and the expiry of patent protection covering several currently used inhaled bronchodilators and corticosteroids will be accompanied by the development of bioequivalent, generic inhaled drugs. Consequently, a broader availability of branded and generic compounds will increase prescription opportunities. Given the time course of COPD, patients are likely to switch drugs and inhalers in daily practice. Switching from one device to another, if not accompanied by appropriate training for the patient, can be associated with poor clinical outcomes and increased use of health care resources. In fact, while it seems reasonable to prescribe generic inhaled drugs to reduce costs, inadequate use of inhaler devices, which is often associated with a poor patient-physician or patient-pharmacist relationship, is one of the most common reasons for failure to achieve COPD treatment outcomes. Further research is needed to quantify, as in asthma, the impact of inappropriate switching of inhalers in patients with COPD and show the outcomes related to the effect of using the same device for delivering inhaled medications.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Broncodilatadores / Costos de los Medicamentos / Enfermedad Pulmonar Obstructiva Crónica / Cumplimiento de la Medicación / Sustitución de Medicamentos / Pulmón Tipo de estudio: Diagnostic_studies / Health_economic_evaluation Límite: Humans Idioma: En Revista: Int J Chron Obstruct Pulmon Dis Año: 2015 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Nueva Zelanda
Texto completo
Añadir a Mi BVS
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Broncodilatadores / Costos de los Medicamentos / Enfermedad Pulmonar Obstructiva Crónica / Cumplimiento de la Medicación / Sustitución de Medicamentos / Pulmón Tipo de estudio: Diagnostic_studies / Health_economic_evaluation Límite: Humans Idioma: En Revista: Int J Chron Obstruct Pulmon Dis Año: 2015 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Nueva Zelanda