Endothelin-1 suppresses insulin-stimulated Akt phosphorylation and glucose uptake via GPCR kinase 2 in skeletal muscle cells.

Horinouchi, Takahiro; Hoshi, Akimasa; Harada, Takuya; Higa, Tsunaki; Karki, Sarita; Terada, Koji; Higashi, Tsunehito; Mai, Yosuke; Nepal, Prabha; Mazaki, Yuichi; Miwa, Soichi

Horinouchi, Takahiro; Hoshi, Akimasa; Harada, Takuya; Higa, Tsunaki; Karki, Sarita; Terada, Koji; Higashi, Tsunehito; Mai, Yosuke; Nepal, Prabha; Mazaki, Yuichi; Miwa, Soichi.

Afiliación

Horinouchi T; Department of Cellular Pharmacology, Hokkaido University Graduate School of Medicine, Sapporo City, Japan.
Hoshi A; Department of Cellular Pharmacology, Hokkaido University Graduate School of Medicine, Sapporo City, Japan.
Harada T; Department of Cellular Pharmacology, Hokkaido University Graduate School of Medicine, Sapporo City, Japan.
Higa T; Department of Cellular Pharmacology, Hokkaido University Graduate School of Medicine, Sapporo City, Japan.
Karki S; Department of Cellular Pharmacology, Hokkaido University Graduate School of Medicine, Sapporo City, Japan.
Terada K; Department of Cellular Pharmacology, Hokkaido University Graduate School of Medicine, Sapporo City, Japan.
Higashi T; Department of Cellular Pharmacology, Hokkaido University Graduate School of Medicine, Sapporo City, Japan.
Mai Y; Department of Cellular Pharmacology, Hokkaido University Graduate School of Medicine, Sapporo City, Japan.
Nepal P; Department of Cellular Pharmacology, Hokkaido University Graduate School of Medicine, Sapporo City, Japan.
Mazaki Y; Department of Cellular Pharmacology, Hokkaido University Graduate School of Medicine, Sapporo City, Japan.
Miwa S; Department of Cellular Pharmacology, Hokkaido University Graduate School of Medicine, Sapporo City, Japan.

Br J Pharmacol ; 173(6): 1018-32, 2016 Mar.

Article en En | MEDLINE | ID: mdl-26660861

Asunto(s)

Endotelina-1/farmacología; Quinasa 2 del Receptor Acoplado a Proteína-G/metabolismo; Glucosa/metabolismo; Insulina/farmacología; Fibras Musculares Esqueléticas/efectos de los fármacos; Proteínas Proto-Oncogénicas c-akt/metabolismo; Animales; Diferenciación Celular; Línea Celular; Quinasa 2 del Receptor Acoplado a Proteína-G/genética; Fibras Musculares Esqueléticas/metabolismo; Músculo Esquelético/citología; Proteína MioD/genética; Mioblastos/citología; Miogenina/genética; Fosforilación; ARN Mensajero/metabolismo; ARN Ribosómico 18S/genética; Ratas

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fibras Musculares Esqueléticas / Endotelina-1 / Proteínas Proto-Oncogénicas c-akt / Quinasa 2 del Receptor Acoplado a Proteína-G / Glucosa / Insulina Límite: Animals Idioma: En Revista: Br J Pharmacol Año: 2016 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido

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