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Target engagement and drug residence time can be observed in living cells with BRET.
Robers, Matthew B; Dart, Melanie L; Woodroofe, Carolyn C; Zimprich, Chad A; Kirkland, Thomas A; Machleidt, Thomas; Kupcho, Kevin R; Levin, Sergiy; Hartnett, James R; Zimmerman, Kristopher; Niles, Andrew L; Ohana, Rachel Friedman; Daniels, Danette L; Slater, Michael; Wood, Monika G; Cong, Mei; Cheng, Yi-Qiang; Wood, Keith V.
Afiliación
  • Robers MB; Promega Corporation, 2800 Woods Hollow Road, Fitchburg, Wisconsin 53711, USA.
  • Dart ML; Promega Corporation, 2800 Woods Hollow Road, Fitchburg, Wisconsin 53711, USA.
  • Woodroofe CC; Promega Biosciences Incorporated, 277 Granada Drive, San Luis Obispo, California 93401, USA.
  • Zimprich CA; Promega Corporation, 2800 Woods Hollow Road, Fitchburg, Wisconsin 53711, USA.
  • Kirkland TA; Promega Biosciences Incorporated, 277 Granada Drive, San Luis Obispo, California 93401, USA.
  • Machleidt T; Promega Corporation, 2800 Woods Hollow Road, Fitchburg, Wisconsin 53711, USA.
  • Kupcho KR; Promega Corporation, 2800 Woods Hollow Road, Fitchburg, Wisconsin 53711, USA.
  • Levin S; Promega Biosciences Incorporated, 277 Granada Drive, San Luis Obispo, California 93401, USA.
  • Hartnett JR; Promega Corporation, 2800 Woods Hollow Road, Fitchburg, Wisconsin 53711, USA.
  • Zimmerman K; Promega Corporation, 2800 Woods Hollow Road, Fitchburg, Wisconsin 53711, USA.
  • Niles AL; Promega Corporation, 2800 Woods Hollow Road, Fitchburg, Wisconsin 53711, USA.
  • Ohana RF; Promega Corporation, 2800 Woods Hollow Road, Fitchburg, Wisconsin 53711, USA.
  • Daniels DL; Promega Corporation, 2800 Woods Hollow Road, Fitchburg, Wisconsin 53711, USA.
  • Slater M; Promega Corporation, 2800 Woods Hollow Road, Fitchburg, Wisconsin 53711, USA.
  • Wood MG; Promega Corporation, 2800 Woods Hollow Road, Fitchburg, Wisconsin 53711, USA.
  • Cong M; Promega Corporation, 2800 Woods Hollow Road, Fitchburg, Wisconsin 53711, USA.
  • Cheng YQ; UNT System College of Pharmacy, Department of Pharmaceutical Sciences, University of North Texas Health Science Center, Fort Worth, Texas, USA.
  • Wood KV; Promega Corporation, 2800 Woods Hollow Road, Fitchburg, Wisconsin 53711, USA.
Nat Commun ; 6: 10091, 2015 Dec 03.
Article en En | MEDLINE | ID: mdl-26631872
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preparaciones Farmacéuticas / Células / Transferencia Resonante de Energía de Fluorescencia / Inhibidores de Histona Desacetilasas Tipo de estudio: Evaluation_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preparaciones Farmacéuticas / Células / Transferencia Resonante de Energía de Fluorescencia / Inhibidores de Histona Desacetilasas Tipo de estudio: Evaluation_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido