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The Role of Dialysis Membranes on Intradialytic Selenium Removal and on Selenium Status in Patients Receiving Renal Replacement Therapy.
Sonikian, Macroui; Dona, Artemisia; Skarakis, Jacob; Trompouki, Sophia; Miha, Theodora; Karatzas, Ioannis; Spiliopoulou, Chara.
Afiliación
  • Sonikian M; Nephrology Department, Konstantopoulion General Hospital, Athens, Greece.
Blood Purif ; 41(1-3): 94-9, 2016.
Article en En | MEDLINE | ID: mdl-26624220
BACKGROUND/AIMS: Dialysis membrane has been implicated in selenium (Se) deficiency in hemodialysis (HD). Intradialytic Se removal into dialysate through different membranes was investigated. METHODS: We studied 19 patients on standard HD with low-flux polysulfone membrane (group A), 10 patients on standard HD with ethylene vinyl alcohol membrane (group B), 12 patients on hemodiafiltration (HDF; group C) and 16 healthy subjects (control group D). Se was measured in blood before and after dialysis session and in effluent dialysate every hour during session. RESULTS: In all patients together, pre-dialysis serum Se levels were lower than those in control group, but, in a separate analysis, only in standard HD. In all patient groups, there was a net Se removal into dialysate but it was greater in HDF patients who, however, had similar pre-dialysis serum Se levels to those in healthy controls. CONCLUSION: An intradialytic Se loss was found with all 3 membrane types, but it is not the principal factor for Se depletion in HD.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Anuria / Selenio / Soluciones para Diálisis / Diálisis Renal Tipo de estudio: Observational_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Blood Purif Año: 2016 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Anuria / Selenio / Soluciones para Diálisis / Diálisis Renal Tipo de estudio: Observational_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Blood Purif Año: 2016 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Suiza