Tongqiao Huoxue Decoction ameliorates learning and memory defects in rats with vascular dementia by up-regulating the Ca(2+)-CaMKII-CREB pathway.

Ge, Chao-Liang; Wang, Xin-Ming; Huang, Zhao-Gang; Xia, Quan; Wang, Ning; Xu, Du-Juan

Ge, Chao-Liang; Wang, Xin-Ming; Huang, Zhao-Gang; Xia, Quan; Wang, Ning; Xu, Du-Juan.

Afiliación

Ge CL; The First Affiliated Hospital of Anhui Medical University of Pharmacy Department, the Third-Grade Pharmaceutical Chemistry Laboratory of State Administration of Traditional Chinese Medicine, Hefei 230022, China. Electronic address: gechaoliang@126.com.
Wang XM; The First Affiliated Hospital of Anhui Medical University of Pharmacy Department, the Third-Grade Pharmaceutical Chemistry Laboratory of State Administration of Traditional Chinese Medicine, Hefei 230022, China.
Huang ZG; The First Affiliated Hospital of Anhui Medical University of Pharmacy Department, the Third-Grade Pharmaceutical Chemistry Laboratory of State Administration of Traditional Chinese Medicine, Hefei 230022, China.
Xia Q; The First Affiliated Hospital of Anhui Medical University of Pharmacy Department, the Third-Grade Pharmaceutical Chemistry Laboratory of State Administration of Traditional Chinese Medicine, Hefei 230022, China.
Wang N; Anhui College of Traditional Chinese Medicine, Anhui Province Key Laboratory of Chinese Medicine Research and Development, Hefei 230038, China.
Xu DJ; The First Affiliated Hospital of Anhui Medical University of Pharmacy Department, the Third-Grade Pharmaceutical Chemistry Laboratory of State Administration of Traditional Chinese Medicine, Hefei 230022, China.

Chin J Nat Med ; 13(11): 823-830, 2015 Nov.

Article en En | MEDLINE | ID: mdl-26614457

Asunto(s)

Calcio/metabolismo; Demencia Vascular/tratamiento farmacológico; Medicamentos Herbarios Chinos/uso terapéutico; Hipocampo/efectos de los fármacos; Discapacidades para el Aprendizaje/tratamiento farmacológico; Trastornos de la Memoria/tratamiento farmacológico; Memoria/efectos de los fármacos; Animales; Proteína Quinasa Tipo 2 Dependiente de Calcio Calmodulina/metabolismo; Proteína de Unión a Elemento de Respuesta al AMP Cíclico/metabolismo; Demencia Vascular/complicaciones; Demencia Vascular/metabolismo; Demencia Vascular/psicología; Medicamentos Herbarios Chinos/farmacología; Femenino; Hipocampo/metabolismo; Discapacidades para el Aprendizaje/etiología; Discapacidades para el Aprendizaje/metabolismo; Masculino; Aprendizaje por Laberinto/efectos de los fármacos; Trastornos de la Memoria/etiología; Trastornos de la Memoria/metabolismo; Fitoterapia; Ratas Sprague-Dawley; Transducción de Señal; Regulación hacia Arriba

Palabras clave

Calcium; Learning and memory; Tongqiao Huoxue Decoction; Vascular dementia

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Medicamentos Herbarios Chinos / Demencia Vascular / Calcio / Hipocampo / Discapacidades para el Aprendizaje / Memoria / Trastornos de la Memoria Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Chin J Nat Med Año: 2015 Tipo del documento: Article Pais de publicación: China

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