Your browser doesn't support javascript.
loading
Androgen receptor CAG and GGN repeat polymorphisms influence performance in boys and girls.
Rodríguez-García, Lorena; Ponce-González, Jesús G; González-Henríquez, Juan J; Rodríguez-González, Francisco G; Díaz-Chico, Bonifacio N; Calbet, Jose A; Dorado, Cecilia; Guadalupe-Grau, Amelia.
Afiliación
  • Rodríguez-García L; Department of Physical Education, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain.
  • Ponce-González JG; Research Institute of Biomedical and Health Sciences, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain.
  • González-Henríquez JJ; Department of Physical Education, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain.
  • Rodríguez-González FG; Research Institute of Biomedical and Health Sciences, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain.
  • Díaz-Chico BN; Research Institute of Biomedical and Health Sciences, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain.
  • Calbet JA; Department of Mathematics, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain.
  • Dorado C; Department of Biochemistry and Physiology, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain.
  • Guadalupe-Grau A; Canary Islands Cancer Research Institute (ICIC), Las Palmas de Gran Canaria, Spain.
J Sports Med Phys Fitness ; 57(1-2): 18-25, 2017.
Article en En | MEDLINE | ID: mdl-26609967
BACKGROUND: Shorter CAG and GGN androgen receptor (AR) repeat polymorphisms are associated with stronger androgen signaling, and therefore, could influence lean mass and exercise performance during growth. METHODS: Physical fitness and body composition were measured by standardized procedures and the length of CAG and GGN repeats was determined by PCR and fragment analysis in 152 boys (11.5±2.6 years; Tanner ≤5) and 116 girls (10.1±3.2 years; Tanner ≤5). Individuals were grouped as CAG short (CAGS) if harboring repeat lengths of ≤21 and CAG long (CAGL) if CAG >21. Moreover, subjects were grouped as GGN short (GGNS) if harboring repeat lengths of ≤23 and GGN long (GGNL) if GGN>23. RESULTS: No significant differences in anthropometrics and body composition were observed between either CAGS and CAGL groups and GGNS and GGNL groups. Boys harboring CAGS completed the 300-meter test faster than their CAGL counterparts. Moreover, girls from the GGNL group showed a significant higher VO2max than those in the GGNS group. CONCLUSIONS: In summary, carrying a short allele of the androgen receptor CAG repeat polymorphism is associated to higher anaerobic performance in boys, whereas long alleles of androgen receptor GGN polymorphisms are associated to higher aerobic capacity in girls.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polimorfismo Genético / Composición Corporal / Receptores Androgénicos / Aptitud Física / Repeticiones de Trinucleótidos Límite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: J Sports Med Phys Fitness Año: 2017 Tipo del documento: Article País de afiliación: España Pais de publicación: Italia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polimorfismo Genético / Composición Corporal / Receptores Androgénicos / Aptitud Física / Repeticiones de Trinucleótidos Límite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: J Sports Med Phys Fitness Año: 2017 Tipo del documento: Article País de afiliación: España Pais de publicación: Italia